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View Structure Prediction Details

Protein: CG4572-PA, CG457...
Organism: Drosophila melanogaster
Length: 482 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG4572-PA, CG457....

Description E-value Query
Range
Subject
Range
gi|54639485, gi|... - gi|54639485|gb|EAL28887.1| GA18267 [Drosophila pseudoobscura pseudoobscura], gi|125777812|ref|XP_001...
gi|54639485|gb|E... - GA18267-PA [Drosophila pseudoobscura], GA18267 [Drosophila pseudoobscura pseudoobscura]
494.0 [0..1] [482..1]

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Predicted Domain #1
Region A:
Residues: [1-79]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTATHCAFL IIATIVAISG AKGVEGERPY RRSFINPYPR YQFFDDGVDP GEPLFLTPLI  60
   61 NNASMSKQEV QKLARVVGS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [80-482]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QFHGVESYSG YLTVDPGFKS NMFFWYFPAE QEPEYAPVVL WLQGGPGASS LFGLFTENGP  60
   61 LELDGHGKLQ KRNYTWSKTH NLIYIDNPVG TGFSFTENDA GYATNEKDVG RNLHEAVMQL 120
  121 YELFEWSNSS GFWVTGESYA GKYVPALAYH IHKVQNAIET RVYVPLKGVA IGNGLSDPLH 180
  181 QLKYGDYLYQ LGLIDEHGLQ SFHDAEAKGA ECIKSHDMEC AFDVFDSLIN GDLTNGSLFS 240
  241 NLTGYNWYYN YLKTHDDDGA NLGEFLQAGA TRRAIHVGNK TFHDLDKENK VELHLKKDIM 300
  301 DSVAPWIAEL LAHYTVCIYS GQLDIIVAYP LTRNYLNQLK FPGSDKYKVA PREVWRVGKE 360
  361 VAGYVKHAGH LVEIMVRNAG HMAPHDQPKW LYMMIDHLTH YKH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 109.0
Match: 1wpxA
Description: Crystal structure of carboxypeptidase Y inhibitor complexed with the cognate proteinase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrolase activity 4.09944423676394 bayes_pls_golite062009
peptidase activity 2.49064988313037 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 2.10044305272656 bayes_pls_golite062009
catalytic activity 1.39629727416851 bayes_pls_golite062009
palmitoyl-(protein) hydrolase activity 1.3250951453762 bayes_pls_golite062009
palmitoyl-CoA hydrolase activity 0.815337671271829 bayes_pls_golite062009
binding 0.780364496307855 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.541803897301601 bayes_pls_golite062009
endopeptidase activity 0.43631945855397 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle