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View Structure Prediction Details

Protein: CG11659-PA
Organism: Drosophila melanogaster
Length: 546 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG11659-PA.

Description E-value Query
Range
Subject
Range
gi|77996178, gi|... - gi|78044063|ref|YP_360551.1| long-chain-fatty-acid--CoA ligase [Carboxydothermus hydrogenoformans Z-...
526.0 [0..3] [536..1]

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Predicted Domain #1
Region A:
Residues: [1-546]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPYTPENSYD NDQKIWSGEP VVKYFDPDLS IGEIIFHEMR RHPQLTAQIS ATEGTVLTRG  60
   61 ELLANAMRLA SYMRSLGLLQ SDIVGLIGRN TTHMLAVAYA CFFNGIAFHS LNITYDRDTI 120
  121 EKIYKVTRPS IIFCDGDEFE KVRSATAELD VKIVTMRNHP LDSIKIDEVV ATPIEENFQP 180
  181 AKLEKGNDQT LAILCSSGTT GTPKAVTITN SRHILAGNYH LTTADVQYSH NTLDWITGLL 240
  241 TTITSGVFST TRIIADNAFD PAFALRIIEE YKVTWTIQPP SSMALMINCP DFETCDLSSL 300
  301 RCYMFGGSRA ALEVQKGIRS RLSHNCLQFV YGFTELGAMA TINCHFDEKT GSVGQLVNGL 360
  361 KMKIKNDDGE SLGPDEIGEV CIMNNQHWSG YYGNEVETRN MRDSLGWYHS GDLGYMDRDG 420
  421 FLYIMDRKKE MLKYQNIMYY PNDIESVISE MPQVAEVCVF GIWSNIFGDE AAAAVVKKLG 480
  481 SELEAQDVVD YVRSRTDSKY KQLNGGAVIV DDLQRSANGK TNRMANKAHF LHLKNRKNIL 540
  541 LSQINT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 111.0
Match: 1ba3A
Description: FIREFLY LUCIFERASE IN COMPLEX WITH BROMOFORM
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
fatty acid ligase activity 4.83067429373059 bayes_pls_golite062009
long-chain fatty acid-CoA ligase activity 4.72692389032116 bayes_pls_golite062009
ligase activity, forming carbon-sulfur bonds 4.4819902512335 bayes_pls_golite062009
acetate-CoA ligase activity 4.48129067128523 bayes_pls_golite062009
acid-thiol ligase activity 2.89129353633634 bayes_pls_golite062009
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) 2.74744781333102 bayes_pls_golite062009
Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activity 2.74744781333102 bayes_pls_golite062009
luciferin monooxygenase activity 2.67396462766343 bayes_pls_golite062009
CoA-ligase activity 2.5960476232329 bayes_pls_golite062009
ligase activity 2.49556073715112 bayes_pls_golite062009
transcription regulator activity 2.31193176808353 bayes_pls_golite062009
catalytic activity 1.83545185797733 bayes_pls_golite062009
binding 1.5312519256537 bayes_pls_golite062009
transcription repressor activity 1.2638869228049 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle