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View Structure Prediction Details

Protein: fru-PE
Organism: Drosophila melanogaster
Length: 955 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for fru-PE.

Description E-value Query
Range
Subject
Range
gi|76678552 - gi|76678552|ref|XP_583095.2| PREDICTED: similar to Zinc finger protein 268 (Zinc finger protein HZF3...
487.0 [0..237] [955..496]

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Predicted Domain #1
Region A:
Residues: [1-99]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMATSQDYFG NPYALFRGPP TTLRPRESPL GVGHPHGHGH LHSHAHAHGH GHAHSHYAAL  60
   61 DLQTPHKRNI ETDVRAPPPP LPPPPLPLPP ASPRYNTDQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [100-217]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GAMDQQFCLR WNNHPTNLTG VLTSLLQREA LCDVTLACEG ETVKAHQTIL SACSPYFETI  60
   61 FLQNQHPHPI IYLKDVRYSE MRSLLDFMYK GEVNVGQSSL PMFLKTAESL QVRGLTDN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 37.0
Match: 2nn2A
Description: No description for 2nn2A was found.

Predicted Domain #3
Region A:
Residues: [218-289]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NNLNYRSDCD KLRDSAASSP TGRGPSNYTG GLGGAGGVAD AMRESRDSLR SRCERDLRDE  60
   61 LTQRSSSSMS ER

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [290-363]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSAAAAAAAA AAAVAAAGGN VNAAAVALGL TTPTGGERSP SVGSASAAAA AAAVAAAVAA  60
   61 AANRSASADG CSDR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [364-473]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSERGTLERT DSRDDLLQLD YSNKDNNNSN SSSTGGNNNN NNNNNNNSSS NNNNSSSNRE  60
   61 RNNSGERERE RERERERDRD RELSTTPVEQ LSSSKRRRKN SSSNCDNSLS 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [474-654]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSHQDRHYPQ DSQANFKSSP VPKTGGSTSE SEDAGGRHDS PLSMTTSVHL GGGGGNVGAA  60
   61 SALSGLSQSL SIKQELMDAQ QQQQHREHHV ALPPDYLPSA ALKLHAEDMS TLLTQHALQA 120
  121 ADARDEHNDA KQLQLDQTDN IDGRVKCFNI KHDRHPDREL DRNHREHDDD PGVIEEVVVD 180
  181 H

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [655-795]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VREMEAGNEH DPEEMKEAAY HATPPKYRRA VVYAPPHPDE EAASGSGSDI YVDGGYNCEY  60
   61 KCKELNMRAI RCSRQQHMMS HYSPHHPHHR SLIDCPAEAA YSPPVANNQA YLASNGAVQQ 120
  121 LDLSTYHGHA NHQLHQHPPS A

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.69897
Match: 2gliA
Description: Five-finger GLI1
Matching Structure (courtesy of the PDB):

Predicted Domain #8
Region A:
Residues: [796-955]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 THPSHSQSSP HYPSASGAGA GAGSVSVSIA GSASGSATSA PASVATSAVS PQPSSSSTGS  60
   61 TSSAAAVAAA AAAAANRRDH NIDYSTLFVQ LSGTLPTLYR CVSCNKIVSN RWHHANIHRP 120
  121 QSHECPVCGQ KFTRRDNMKA HCKIKHADIK DRFFSHYVHM 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 32.69897
Match: 2i13A
Description: No description for 2i13A was found.

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