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View Structure Prediction Details

Protein: fru-PE
Organism: Drosophila melanogaster
Length: 955 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for fru-PE.

Description E-value Query
Range
Subject
Range
gi|76678552 - gi|76678552|ref|XP_583095.2| PREDICTED: similar to Zinc finger protein 268 (Zinc finger protein HZF3...
487.0 [0..237] [955..496]

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Predicted Domain #1
Region A:
Residues: [1-99]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMATSQDYFG NPYALFRGPP TTLRPRESPL GVGHPHGHGH LHSHAHAHGH GHAHSHYAAL  60
   61 DLQTPHKRNI ETDVRAPPPP LPPPPLPLPP ASPRYNTDQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [100-217]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GAMDQQFCLR WNNHPTNLTG VLTSLLQREA LCDVTLACEG ETVKAHQTIL SACSPYFETI  60
   61 FLQNQHPHPI IYLKDVRYSE MRSLLDFMYK GEVNVGQSSL PMFLKTAESL QVRGLTDN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 37.0
Match: 2nn2A
Description: No description for 2nn2A was found.

Predicted Domain #3
Region A:
Residues: [218-289]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NNLNYRSDCD KLRDSAASSP TGRGPSNYTG GLGGAGGVAD AMRESRDSLR SRCERDLRDE  60
   61 LTQRSSSSMS ER

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [290-363]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSAAAAAAAA AAAVAAAGGN VNAAAVALGL TTPTGGERSP SVGSASAAAA AAAVAAAVAA  60
   61 AANRSASADG CSDR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [364-473]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSERGTLERT DSRDDLLQLD YSNKDNNNSN SSSTGGNNNN NNNNNNNSSS NNNNSSSNRE  60
   61 RNNSGERERE RERERERDRD RELSTTPVEQ LSSSKRRRKN SSSNCDNSLS 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [474-654]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSHQDRHYPQ DSQANFKSSP VPKTGGSTSE SEDAGGRHDS PLSMTTSVHL GGGGGNVGAA  60
   61 SALSGLSQSL SIKQELMDAQ QQQQHREHHV ALPPDYLPSA ALKLHAEDMS TLLTQHALQA 120
  121 ADARDEHNDA KQLQLDQTDN IDGRVKCFNI KHDRHPDREL DRNHREHDDD PGVIEEVVVD 180
  181 H

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [655-795]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VREMEAGNEH DPEEMKEAAY HATPPKYRRA VVYAPPHPDE EAASGSGSDI YVDGGYNCEY  60
   61 KCKELNMRAI RCSRQQHMMS HYSPHHPHHR SLIDCPAEAA YSPPVANNQA YLASNGAVQQ 120
  121 LDLSTYHGHA NHQLHQHPPS A

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.69897
Match: 2gliA
Description: Five-finger GLI1
Matching Structure (courtesy of the PDB):

Predicted Domain #8
Region A:
Residues: [796-955]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 THPSHSQSSP HYPSASGAGA GAGSVSVSIA GSASGSATSA PASVATSAVS PQPSSSSTGS  60
   61 TSSAAAVAAA AAAAANRRDH NIDYSTLFVQ LSGTLPTLYR CVSCNKIVSN RWHHANIHRP 120
  121 QSHECPVCGQ KFTRRDNMKA HCKIKHADIK DRFFSHYVHM 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 32.69897
Match: 2i13A
Description: No description for 2i13A was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle