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View Structure Prediction Details

Protein: Prx5-PB, Prx5-PA
Organism: Drosophila melanogaster
Length: 190 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Prx5-PB, Prx5-PA.

Description E-value Query
Range
Subject
Range
gi|21912927 - gi|21912927|emb|CAC84143.2| thioredoxin peroxidase [Nicotiana tabacum]
166.0 [0..1] [189..43]

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Predicted Domain #1
Region A:
Residues: [1-190]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRVLSCKFLG RVVNSALPQQ IISLRSLSKT SAAMVKVGDS LPSVDLFEDS PANKINTGDL  60
   61 VNGKKVIIFG VPGAFTPGCS KTHLPGYVSS ADELKSKQGV DEIVCVSVND PFVMSAWGKE 120
  121 HGAAGKVRLL ADPAGGFTKA LDVTIDLPPL GGVRSKRYSL VVENGKVTEL NVEPDGTGLS 180
  181 CSLANNIGKK 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 29.69897
Match: 1oc3A
Description: HUMAN PEROXIREDOXIN 5
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
antioxidant activity 3.8464796631544 bayes_pls_golite062009
peroxidase activity 3.43831566988273 bayes_pls_golite062009
oxidoreductase activity, acting on peroxide as acceptor 3.43831566988273 bayes_pls_golite062009
glutathione peroxidase activity 2.56524997297011 bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors 2.23310780102446 bayes_pls_golite062009
peroxiredoxin activity 2.12777217096121 bayes_pls_golite062009
thioredoxin peroxidase activity 1.96134566495756 bayes_pls_golite062009
protein disulfide oxidoreductase activity 1.47769936616412 bayes_pls_golite062009
disulfide oxidoreductase activity 1.32811008894503 bayes_pls_golite062009
binding 1.25802922431343 bayes_pls_golite062009
selenium binding 1.1082524159827 bayes_pls_golite062009
catalytic activity 0.672192331361968 bayes_pls_golite062009
transcription regulator activity 0.52671047749426 bayes_pls_golite062009
protein binding 0.134341907247724 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH 0.0801269279614203 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle