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View Structure Prediction Details

Protein: CREG-PC
Organism: Drosophila melanogaster
Length: 173 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CREG-PC.

Description E-value Query
Range
Subject
Range
gi|3550341 - gi|3550341|gb|AAC34860.1| cellular repressor of E1A-stimulated genes CREG [Drosophila melanogaster]
187.0 [0..1] [173..1]

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Predicted Domain #1
Region A:
Residues: [1-173]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTFHSLLFA LILALVSLDP SSGYSRRKDE RIIREYKREQ ELNHAKIARD LVHRANWAAV  60
   61 GSLSTNERVK GYPMVNIISI DDSDANNRST GRIRFLLTDL DFTGPDWQKD NKVTLLFSDE 120
  121 QTLRCKEGGK DPMEPTCARS MISGQVKKLT ISTFANWKLA ISLFWTSMEV LIK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 41.69897
Match: 1xhnA
Description: The crystal structure of Cellular Repressor of E1A-stimulated Genes (CREG)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 2.31887334511829 bayes_pls_golite062009
transcription repressor activity 1.64863812936899 bayes_pls_golite062009
binding 1.60534132207804 bayes_pls_golite062009
catalytic activity 0.660906721832294 bayes_pls_golite062009
transcription factor binding 0.463016643940605 bayes_pls_golite062009
protein binding 0.222179736788716 bayes_pls_golite062009
transcription corepressor activity 0.00754193540843673 bayes_pls_golite062009

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