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View Structure Prediction Details

Protein: FBpp0293269, SF2-PA
Organism: Drosophila melanogaster
Length: 255 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0293269, SF2-PA.

Description E-value Query
Range
Subject
Range
gi|73976787 - gi|73976787|ref|XP_857499.1| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 2 ...
175.0 [0..7] [255..191]
PABP2_ARATH - Polyadenylate-binding protein 2 OS=Arabidopsis thaliana GN=PAB2 PE=1 SV=1
171.0 [0..7] [254..215]
gi|13560783 - gi|13560783|gb|AAK30205.1|AF349964_1 poly(A)-binding protein [Daucus carota]
171.0 [0..1] [254..213]
gi|1082703, gi|6... - gi|693937|emb|CAA88401.1| polyadenylate binding protein II [Homo sapiens], pir||S52491 polyadenylate...
169.0 [0..7] [255..166]
gi|76689285 - gi|76689285|ref|XP_881509.1| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 2 ...
168.0 [0..7] [254..191]

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Predicted Domain #1
Region A:
Residues: [1-98]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSRNECRIY VGNLPPDIRT KDIQDLFHKF GKVTFVDLKN RRGPPFAFVE FEDARDADDA  60
   61 VKARDGYDYD GYRLRVEFPR GGGPGSYRGG NRNDRSRD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.221849
Match: 1x4aA
Description: Solution structure of RRM domain in splicing factor SF2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.950788308762215 bayes_pls_golite062009
nucleic acid binding 0.29562225149076 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [99-255]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGGRMGGRGP PAKRSQYRVM VTGLPASGSW QDLKDHMREA GDVCFADTYK DGSGVVEFLR  60
   61 HEDMKYAIKK LDDSRFRSHE GEVAYIRVRE DSGDNDRGGG GGGSGGGGGG SGGGGSRDYR 120
  121 DRSRSRSFSS RPRRRGTPTY SPVRRQSYSR SRSRSNY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.39794
Match: 1jmtA
Description: U2AF35 (35 KDa subunit)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.950788308762215 bayes_pls_golite062009
nucleic acid binding 0.29562225149076 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle