YRC Public Data Repository - Protein Structure Prediction

Protein:	sra-PA, FBpp0310844
Organism:	Drosophila melanogaster
Length:	292 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for sra-PA, FBpp0310844.

Description	E-value	Query Range	Subject Range
gi\|74001209 - gi\|74001209\|ref\|XP_849295.1\| PREDICTED: similar to calcipressin 1 isoform a isoform 1 [Canis familia...	323.0	[0..90]	[292..29]
gi\|193787288, gi... - gi\|33620725\|ref\|NP_004405.3\| calcipressin 1 isoform a [Homo sapiens], gi\|33149232\|gb\|AAP96743.1\| cal...	319.0	[0..90]	[290..32]
gi\|114684002 - gi\|114684002\|ref\|XP_001167915.1\| PREDICTED: calcipressin 1 isoform 5 [Pan troglodytes]	318.0	[0..90]	[290..32]
gi\|109065409 - gi\|109065409\|ref\|XP_001088613.1\| PREDICTED: similar to calcipressin 1 isoform a isoform 2 [Macaca mu...	316.0	[0..90]	[290..29]
gi\|74145094, gi\|... - gi\|74145094\|dbj\|BAE27416.1\| unnamed protein product [Mus musculus], gi\|33149234\|gb\|AAP96744.1\| calci...	314.0	[0..90]	[290..29]
RCAN1_RAT - Calcipressin-1 OS=Rattus norvegicus GN=Rcan1 PE=2 SV=1	307.0	[0..106]	[290..1]
gi\|125777719, gi... - gi\|54639453\|gb\|EAL28855.1\| GA19337-PA [Drosophila pseudoobscura], gi\|125777719\|ref\|XP_001359704.1\| G...	307.0	[0..55]	[292..1]
gi\|50729949 - gi\|50729949\|ref\|XP_416719.1\| PREDICTED: similar to DSCR1-like protein [Gallus gallus]	306.0	[0..106]	[290..44]

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Predicted Domain #1

Region A:
Residues: [1-104]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDAAKSNNN ASADAPDPTT PDATGEADAA NAATPTTPRG NHNNNNSANG RSKNKLKSTQ  60
   61 NSSGGGSIDK LSPDQDIFIN AADGLPNQHP SLPKEGDVDS DTEP

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [105-292]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EVDADSFDDL PTSIIVTNIH SEVFANPELK HAMEELFRTF SESATFQWLR SFRRLRVNYD  60
   61 NAIAAANARI KLHQYEFNKK TVITCYFAQP VTPVSNKNLQ PPAPVKQFLI SPPASPPAGW 120
  121 EPREEGEPLV NHDLLAALAS LTPGESHELH PQSEDQPAII VHTAMLAETG PGLQVKAPIV 180
  181 QTKCPERA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	34.522879
Match:	1weyA
Description:	Solution structure of RRM domain in calcipressin 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
nucleic acid binding	4.11118333721636	bayes_pls_golite062009
binding	3.64400841800969	bayes_pls_golite062009
RNA binding	2.45916448091535	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	1.9432590957792	bayes_pls_golite062009
hydrolase activity	1.69824301409862	bayes_pls_golite062009
mRNA binding	1.62410365165765	bayes_pls_golite062009
transcription regulator activity	1.24650529385826	bayes_pls_golite062009
DNA binding	1.23082363146877	bayes_pls_golite062009
protein binding	1.12215421354121	bayes_pls_golite062009
transcription factor activity	0.426324573266235	bayes_pls_golite062009
sequence-specific DNA binding	0.0605038543305221	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: