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View Structure Prediction Details

Protein: Rbp4-PA
Organism: Drosophila melanogaster
Length: 428 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Rbp4-PA.

Description E-value Query
Range
Subject
Range
gi|76689281 - gi|76689281|ref|XP_881384.1| PREDICTED: similar to Polyadenylate-binding protein 4 (Poly(A)-binding ...
248.0 [0..3] [424..154]

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Predicted Domain #1
Region A:
Residues: [1-224]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDAGNCASSA CLGDCKGDGK TAIKEEGYEH LRKIFIGGLS TQTTVETLRG FFSQFGIVAD  60
   61 AVVLRDPVSN HSRGFGFVTY VDPKSVEIVQ RARPHTIDNK IVETKHALPR QDFKRGGGVG 120
  121 SVVGSFGCEA GFMNSKRIFL GGLKEYHDEN IVREYFSQFG PVASVKLLMD RETGRQRAFG 180
  181 FLEFVDPSSA EKALAPRKHW ILQTLVEVKR STQKADRRFR FPIF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 55.522879
Match: 1pgzA
Description: Crystal Structure of UP1 Complexed With d(TTAGGGTTAG(6-MI)G); A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6-MI)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 4.63987691433124 bayes_pls_golite062009
mRNA binding 3.54495985180603 bayes_pls_golite062009
nucleic acid binding 2.94848701812661 bayes_pls_golite062009
binding 2.41127885655304 bayes_pls_golite062009
1.71820051628117 bayes_pls_golite062009
single-stranded RNA binding 1.46469774223879 bayes_pls_golite062009
poly-pyrimidine tract binding 0.862661444935922 bayes_pls_golite062009
protein binding 0.42571879933058 bayes_pls_golite062009
mRNA 3'-UTR binding 0.366474768004238 bayes_pls_golite062009
transcription regulator activity 0.0376525951141159 bayes_pls_golite062009
DNA binding 0.017779252073686 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [225-428]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSVRAGYIPP QPATADSYNY NNPNYNPYLA QSVLPPSAFT NGWAHYVIPM APKPTPGQNM  60
   61 AASLPSQQLA EHSLNGHGPD MWSSYPKTGI YSAQEWTSSK VAEWGPKAGH KHAQTSTNDR 120
  121 AKIDLKELQA ATFNNKLDFG ARGDADRMSG AGLGLGLTGG AAVGVGAIKK WPTQDYKVFK 180
  181 PAKSPTNGVI PKIGKEATTP PYGI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.522879
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle