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View Structure Prediction Details

Protein: mthl11-PA
Organism: Drosophila melanogaster
Length: 510 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mthl11-PA.

Description E-value Query
Range
Subject
Range
FBpp0297746, mth-PA - The gene methuselah is referred to in FlyBase by the symbol Dmel\mth (CG6936, FBgn0023000). It is a ...
290.0 [0..3] [497..6]

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Predicted Domain #1
Region A:
Residues: [1-196]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGMFRVEYLL LGILVIGVRS RDIPNCDFFD TVQLRESEKL CNGSYRYEDV VIPAKLTGKY  60
   61 DYEIDYDGDR VSVPKHIRGC VCKLKTCIRF CCHHKKLMAG NLCSQDVYEN LTYEYTLDIT 120
  121 QLNGSVIKKH VLNDMVVQQD LPLPCERHYS LDAETSTYDM WSLYENGSLF RHFDQRYLSK 180
  181 QEFCLQPNPT STGKNY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 52.221849
Match: 1fjrA
Description: Methuselah ectodomain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
G-protein coupled receptor activity 7.48253527316663 bayes_pls_golite062009
transmembrane receptor activity 5.76968261800439 bayes_pls_golite062009
receptor activity 5.47976284348283 bayes_pls_golite062009
signal transducer activity 4.51388461085202 bayes_pls_golite062009
molecular transducer activity 4.51388461085202 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [197-510]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SLIVAFNCIQ KPSMKMAYGR FECVRKSRLS NASIPVKFSS VFFMVITIAA YLWLPKFRSL  60
   61 HGKCCNLYFI CLAITFLLNV ISLFGIFELK TPICYLTGYA GYFTVMATFL WLSVISFDVW 120
  121 RRFAMRKFQV FYKNKRSSFF NYNIIVWSSA GLLTCIIFLV DQFVETNLDN PYNPAVGVFS 180
  181 CWIFTNGWSA TFYFYAPLAI LIILNCASFF LTTRYIYVEN KQNQKVLNNS EPQKLSRNHA 240
  241 NYRIYFRLFI IMGGSWFLEI IAFICEMENM WKPLIILNDY INCSQGIIIF VATFCNHEMF 300
  301 RLIRKRWVFC DSTP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 56.522879
Match: 1f88A
Description: Rhodopsin
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
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