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View Structure Prediction Details

Protein: ps-PH, ps-PG, ps...
Organism: Drosophila melanogaster
Length: 572 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ps-PH, ps-PG, ps....

Description E-value Query
Range
Subject
Range
gi|125773159|ref... - GA20847-PA [Drosophila pseudoobscura], GA20847 [Drosophila pseudoobscura pseudoobscura]
gi|54637571, gi|... - gi|54637571|gb|EAL26973.1| GA20847 [Drosophila pseudoobscura pseudoobscura], gi|125773159|ref|XP_001...
321.0 [0..12] [572..12]

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Predicted Domain #1
Region A:
Residues: [1-247]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEDATMETC PSPETGDSRK RPLDSDPENE QTKRSHFSSG ESVCSGIEVE IENNNNNHIH  60
   61 HGETTYHMKI LVPAVASGAI IGKGGETIAS LQKDTGARVK MSKSHDFYPG TTERVCLITG 120
  121 STEAIMVVME FIMDKIREKP DLTNKIVDTD SKQTQERDKQ VKILVPNSTA GMIIGKGGAF 180
  181 IKQIKEESGS YVQISQKPTD VSLQERCITI IGDKENNKNA CKMILSKIVE DPQSGTCLNV 240
  241 SYADVSG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 33.522879
Match: 2annA
Description: No description for 2annA was found.

Predicted Domain #2
Region A:
Residues: [248-468]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PVANFNPTGS PYATNQNAIN SSTASLNSTL GTTIGGANSA ASLLVNGTGI NLSINLGSPN  60
   61 PAPNLAVATQ LLEHIKVAMR GSGYSETVTN EVVAALSVLA KYGVLGMGVG VSHTNGAHST 120
  121 LGNFLGVTTL DQQTAAAASA ATASNVFGAV GQVNLEQYAA AVASAAAASR PTQSQLDAAA 180
  181 VQFDPFRHLG SATAPAATPV SLNNNSFGLT ATTGTATTAQ L

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [469-572]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGLSKSPTPG DLSSKDSKNV EVPEVIIGAI LGPSGRSLVE IQHVSGANVQ ISKKGIFAPG  60
   61 TRNRIVTITG QPSAIAKAQY LIEQKINEEE TKRARQIPLT TVVN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.69897
Match: 1ec6A
Description: Neuro-oncological ventral antigen 2, nova-2, KH3
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 5.18414740305744 bayes_pls_golite062009
mRNA binding 3.82977088614136 bayes_pls_golite062009
nucleic acid binding 3.68444148122352 bayes_pls_golite062009
binding 2.8667878224392 bayes_pls_golite062009
transcription regulator activity 1.43703138180882 bayes_pls_golite062009
DNA binding 1.20852534725468 bayes_pls_golite062009
1.02980840568405 bayes_pls_golite062009
poly-pyrimidine tract binding 0.63404501189528 bayes_pls_golite062009
mRNA 3'-UTR binding 0.489176583045793 bayes_pls_golite062009
protein binding 0.468975312217329 bayes_pls_golite062009
transcription factor activity 0.386248501195543 bayes_pls_golite062009
catalytic activity 0.113112541746059 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle