






| Protein: | HP1e-PA |
| Organism: | Drosophila melanogaster |
| Length: | 174 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HP1e-PA.
| Description | E-value | Query Range |
Subject Range |
|
|
186.0 | [0..10] | [171..272] |
|
Region A: Residues: [1-174] |
1 11 21 31 41 51
| | | | | |
1 MDSDADGGET VSNFSENSTD FEETEEYIVE RILDRRHYMG QLQYLVKWLD YSDEDNTWES 60
61 AADLDCHSLI DSIESQKSLK RGQELNNQYE TKAKRLKIDP CLVVDSPFNH GFTAQEILKG 120
121 AKNNGEISFL IRFWHLDQPQ VVPSGIAYVE IPQMVLKFYE NHCNFHDYLN NYIS
|
| Detection Method: | |
| Confidence: | 16.221849 |
| Match: | 2b2tA |
| Description: | Tandem chromodomains of human CHD1 complexed with Histone H3 Tail containing trimethyllysine 4 and phosphothreonine 3 |
Matching Structure (courtesy of the PDB):![]() |
|
| Term | Confidence | Notes |
| transcription repressor activity | 4.08500855631983 | bayes_pls_golite062009 |
| transcription regulator activity | 3.64390820819794 | bayes_pls_golite062009 |
| methylated histone residue binding | 3.42338304360938 | bayes_pls_golite062009 |
| chromatin binding | 3.1924157640698 | bayes_pls_golite062009 |
| binding | 3.06758476214113 | bayes_pls_golite062009 |
| protein binding | 2.66728689880621 | bayes_pls_golite062009 |
| nucleic acid binding | 2.19167058827256 | bayes_pls_golite062009 |
| DNA binding | 2.05514577638135 | bayes_pls_golite062009 |
| histone binding | 2.00388175060339 | bayes_pls_golite062009 |
| transcription activator activity | 1.46529895769882 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 1.10020047862576 | bayes_pls_golite062009 |
| DNA-dependent ATPase activity | 0.998957812785999 | bayes_pls_golite062009 |
| general transcriptional repressor activity | 0.75184432495983 | bayes_pls_golite062009 |
| DNA helicase activity | 0.726970683178132 | bayes_pls_golite062009 |
| ATP-dependent DNA helicase activity | 0.494788451379878 | bayes_pls_golite062009 |
| transcription corepressor activity | 0.294457188332415 | bayes_pls_golite062009 |
| catalytic activity | 0.14067200158938 | bayes_pls_golite062009 |