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View Structure Prediction Details

Protein: Nmdmc-PB
Organism: Drosophila melanogaster
Length: 309 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Nmdmc-PB.

Description E-value Query
Range
Subject
Range
gi|116127953, gi... - gi|118785396|ref|XP_314619.2| ENSANGP00000022519 [Anopheles gambiae str. PEST], gi|116127953|gb|EAA4...
377.0 [0..2] [309..2]

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Predicted Domain #1
Region A:
Residues: [1-309]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRFTSNMAQI IDGKAIAQEV RTQLAHELKG MEAAGYPKPH LTAVIVGEDP ASEKYVANKM  60
   61 VACREVGISS ETKRLPASTT QEELLQLIAD LNKDPQVTGI LVQLPVPEHI NERTICNAVD 120
  121 VDKDVDGFNE VNIGRTALDM EANIPATPLG VKRLLEHMKI ETLGRNAVVV GRSKNVSLPM 180
  181 AILLHADGKY ATKAMDATVT ICHRYTPPKE LARHCRQADI IVVAVGKPGL ITKDMVKPGA 240
  241 CVIDVGINRI KDESTGQFKL VGDVDFEEVR QVAGHITPVP GGVGPMTVAM LMHNTLKAAR 300
  301 KQFDDRKSS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 97.69897
Match: 1b0aA
Description: Methylenetetrahydrofolate dehydrogenase/cyclohydrolase; Tetrahydrofolate dehydrogenase/cyclohydrolase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
oxidoreductase activity 3.54983447672782 bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors 2.66605122152932 bayes_pls_golite062009
malate dehydrogenase activity 2.43636049081724 bayes_pls_golite062009
catalytic activity 2.0643953589843 bayes_pls_golite062009
transcription regulator activity 1.95832530533882 bayes_pls_golite062009
methenyltetrahydrofolate cyclohydrolase activity 1.95551536198286 bayes_pls_golite062009
DNA binding 1.70073234884672 bayes_pls_golite062009
binding 1.57522146187634 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1.54527841865655 bayes_pls_golite062009
nucleic acid binding 1.47211855405194 bayes_pls_golite062009
malic enzyme activity 1.39067036188188 bayes_pls_golite062009
transcription factor activity 0.9895904275677 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor 0.66392365734856 bayes_pls_golite062009
cyclohydrolase activity 0.129148522173579 bayes_pls_golite062009
ligase activity 0.0191278372003161 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle