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View Structure Prediction Details

Protein: CG2993-PA
Organism: Drosophila melanogaster
Length: 511 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG2993-PA.

Description E-value Query
Range
Subject
Range
gi|125777968|ref... - GA15564-PA [Drosophila pseudoobscura], GA15564 [Drosophila pseudoobscura pseudoobscura]
gi|54639537, gi|... - gi|54639537|gb|EAL28939.1| GA15564 [Drosophila pseudoobscura pseudoobscura], gi|125777968|ref|XP_001...
302.0 [0..1] [511..1]

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Predicted Domain #1
Region A:
Residues: [1-361]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPIECLISFD NNPQGVYYAG QELSGVVDLS VDATKRIKGI HVTVSGYAKI RWIKKGYPRD  60
   61 SERAMCRAYR SYLSSRSYVL GSCANNSSID WPAGEYSYTF HVILPDNLPT SFDGKYGQIH 120
  121 YEIITTIERA ARHPKVFKLP FTVIQPLDLN ADAIYRVPLE ILDRKRFWSF CCPTGPLTVK 180
  181 FSTPYCGYAP GQKIHFVLYI NNESSIDIIE CEVKLKQEVS YESHDPQHEY RYDKHLIARK 240
  241 QFGNVLRWSR KVYRGYLDLP SIPPTSVKPT CPISVNYSIK IIVNPTEFHW KLKLKIPLTI 300
  301 GSIPIMDGPE ALLRFNRQQQ QHQVVSQNLQ MSTQQRQRDR DRDRDMNVDR ERDRDRDRDR 360
  361 I

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 46.69897
Match: 1cf1A
Description: Arrestin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.16794183103103 bayes_pls_golite062009
transporter activity 0.91575626181147 bayes_pls_golite062009
protein binding 0.80731472263402 bayes_pls_golite062009
transmembrane transporter activity 0.79859394765741 bayes_pls_golite062009
substrate-specific transporter activity 0.54937609432488 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.44156924045904 bayes_pls_golite062009
ion transmembrane transporter activity 0.24999576011985 bayes_pls_golite062009
metal ion transmembrane transporter activity 0.22863314984066 bayes_pls_golite062009
cation transmembrane transporter activity 0.16509232167563 bayes_pls_golite062009
potassium channel activity 0.0818357049046399 bayes_pls_golite062009
voltage-gated cation channel activity 0.0384562692389601 bayes_pls_golite062009
voltage-gated ion channel activity 0.0274514394602403 bayes_pls_golite062009
voltage-gated channel activity 0.0155870232872002 bayes_pls_golite062009
voltage-gated potassium channel activity 0.00646167451922031 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [362-511]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SASVQQRRIS SINNNNNNHG RLVGGLLPTN SNMNMITNVS PTPTSSTPSS TPTTAALRPT  60
   61 AMPAILVTSD SDNPPDYIPM MPPSYEDAMA LSEKFSDDTE FLTNVSMSSI LSAQADVTTS 120
  121 EPFKPRYPVY YDYETPTIPP GSDDSNESDT 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle