| Protein: | ksr-PA, FBpp0310... |
| Organism: | Drosophila melanogaster |
| Length: | 966 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ksr-PA, FBpp0310....
| Description | E-value | Query Range |
Subject Range |
|
|
647.0 | [0..1] | [966..1] |
|
Region A: Residues: [1-186] |
1 11 21 31 41 51
| | | | | |
1 MSSNNNAPAS APDTGSTNAN DPISGSLSVD SNLVIIQDMI DLSANHLEGL RTQCAISSTL 60
61 TQQEIRCLES KLVRYFSELL LAKMRLNERI PANGLVPHTT GNELRQWLRV VGLSQGTLTA 120
121 CLARLTTLEQ SLRLSDEEIR QLLADSPSQR EEEELRRLTR AMQNLRKCME SLESGTAASN 180
181 NDPEQW
|
| Detection Method: |  |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [187-345] |
1 11 21 31 41 51
| | | | | |
1 HWDSWDRPTH IHRGSVGNIG LGNNSTASPR THHRQHGVKG KNSALANSTN FKSGRQSPSA 60
61 TEELNSTQGS QLTLTLTPSP PNSPFTPSSG LSSSLNGTPQ RSRGTPPPAR KHQTLLSQSH 120
121 VQVDGEQLAR NRLPTDPSPD SHSSTSSDIF VDPNTNASS
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [346-450] |
1 11 21 31 41 51
| | | | | |
1 GGSSSNVLMV PCSPGVGHVG MGHAIKHRFT KALGFMATCT LCQKQVFHRW MKCTDCKYIC 60
61 HKSCAPHVPP SCGLPREYVD EFRHIKEQGG YASLPHVHGA AKGSP
|
| Detection Method: | |
| Confidence: | 4.69897 |
| Match: | 1xa6A |
| Description: | Crystal Structure of the Human Beta2-Chimaerin |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 2.79128751898373 | bayes_pls_golite062009 |
| GTPase regulator activity | 2.70614727793157 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 2.68579854252375 | bayes_pls_golite062009 |
| guanyl-nucleotide exchange factor activity | 2.06038764955701 | bayes_pls_golite062009 |
| enzyme regulator activity | 1.9750017471254 | bayes_pls_golite062009 |
| small GTPase regulator activity | 1.95738547986197 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 1.76952905409847 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.65104526054036 | bayes_pls_golite062009 |
| protein kinase activity | 1.62921423829738 | bayes_pls_golite062009 |
| kinase activity | 1.56666023161051 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.52955027516214 | bayes_pls_golite062009 |
| protein binding | 1.29100556128076 | bayes_pls_golite062009 |
| signal transducer activity | 1.25507073225414 | bayes_pls_golite062009 |
| molecular transducer activity | 1.25507073225414 | bayes_pls_golite062009 |
| Ras GTPase activator activity | 1.09070479183477 | bayes_pls_golite062009 |
| transcription regulator activity | 1.08577758274384 | bayes_pls_golite062009 |
| Ras guanyl-nucleotide exchange factor activity | 0.958295643211986 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.956859696337723 | bayes_pls_golite062009 |
| transferase activity | 0.751543629515057 | bayes_pls_golite062009 |
| GTPase activator activity | 0.717730683557543 | bayes_pls_golite062009 |
| nucleic acid binding | 0.604021689968387 | bayes_pls_golite062009 |
| DNA binding | 0.418154636457321 | bayes_pls_golite062009 |
| enzyme activator activity | 0.298334474872045 | bayes_pls_golite062009 |
| catalytic activity | 0.194464246602439 | bayes_pls_golite062009 |
|
Region A: Residues: [451-647] |
1 11 21 31 41 51
| | | | | |
1 LVKKSTLGKP LHQQHGDSSS PSSSCTSSTP SSPALFQQRE RELDQAGSSS SANLLPTPSL 60
61 GKHQPSQFNF PNVTVTSSGG SGGVSLISNE PVPEQFPTAP ATANGGLDSL VSSSNGHMSS 120
121 LIGSQTSNAS TAATLTGSLV NSTTTTSTCS FFPRKLSTAG VDKRTPFTSE YTDTHKSNDS 180
181 DKTVSLSGSA STDSDRT
|
| Detection Method: | |
| Confidence: | 14.154902 |
| Match: | 1x27A |
| Description: | Crystal Structure of Lck SH2-SH3 with SH2 binding site of p130Cas |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 3.06905798270146 | bayes_pls_golite062009 |
| protein binding | 2.08632303609243 | bayes_pls_golite062009 |
| signal transducer activity | 1.34867629228264 | bayes_pls_golite062009 |
| molecular transducer activity | 1.34867629228264 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 0.83493091348808 | bayes_pls_golite062009 |
| receptor binding | 0.351326788023913 | bayes_pls_golite062009 |
|
Region A: Residues: [648-966] |
1 11 21 31 41 51
| | | | | |
1 PVRVDSTEDG DSGQWRQNSI SLKEWDIPYG DLLLLERIGQ GRFGTVHRAL WHGDVAVKLL 60
61 NEDYLQDEHM LETFRSEVAN FKNTRHENLV LFMGACMNPP YLAIVTSLCK GNTLYTYIHQ 120
121 RREKFAMNRT LLIAQQIAQG MGYLHAREII HKDLRTKNIF IENGKVIITD FGLFSSTKLL 180
181 YCDMGLGVPH NWLCYLAPEL IRALQPEKPR GECLEFTPYS DVYSFGTVWY ELICGEFTFK 240
241 DQPAESIIWQ VGRGMKQSLA NLQSGRDVKD LLMLCWTYEK EHRPQFARLL SLLEHLPKKR 300
301 LARSPSHPVN LSRSAESVF
|
| Detection Method: | |
| Confidence: | 63.221849 |
| Match: | 2fb8A |
| Description: | No description for 2fb8A was found. |
