YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: Hcs-PA
Organism: Drosophila melanogaster
Length: 1041 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Hcs-PA.

Description E-value Query
Range
Subject
Range
gi|66565539 - gi|66565539|ref|XP_395226.2| PREDICTED: similar to CG14670-PA, partial [Apis mellifera]
588.0 [0..40] [1039..2]

Back

Predicted Domain #1
Region A:
Residues: [1-150]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLTLYYVSAT VLQSWRIQKA CSKIAEHLAQ PSSIAFYTLQ SGSDDGFDPA LASSELCCNR  60
   61 NAAKVTDILW LHANQRGCCL RPLQTLHITP WISFPPAPSL LPFSYAADTL TPASTPTEAD 120
  121 VPRQQRVSLS AQGEERMQLL LEADIEPLQR 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [151-393]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSSEDTSAVR LEDYGKLIAW KIDSHLAVLI ETDVEHFTKL LITTFLRNNL CINDQLPLLR  60
   61 IESVQREGDP QPFELLAKHL KRQSRISVGL DKDGWKKHME DLRAVGVLAH QATEFEYQRN 120
  121 RSEGRTKSDP TTHDQRPTSE LLAKAVAVVE PTNKAYLSPA RTTEASLKAE AKGTSTKPFP 180
  181 TKSDAKPATL AKSEGTPATS KEDSKLTPTK GALKTSELEK LAAVQAAQQQ KKEAVQVSPV 240
  241 KAA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [394-512]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FLAKPPMLSK HDEPDKASDQ PTKPRKSFEA VKPLNSPPSS RAAPSRPVLQ RNKDSLQDAK  60
   61 PLNVLVYSDS ASARESTLAT LQQLLERNVY TIYPLMPQQA AQKYWTEQTA LLVVCGSVA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [513-707]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HGIGQILVDY FLQGGKVLSL CSDILHFVLP NYRTAEVREH ELVQFSYDKW QRVKMMHHIF  60
   61 CYQPSPVKKH FSTDSEESTK SHSRKPSMEL KDLAGHSHNL DVHVLGTEET WNTPSLMLAK 120
  121 SLQSGGKAVF SQVHLEMNPS EFESDETKYS ILKQNERTRL EIFADLLGKY LDVQVRGGDG 180
  181 VDQPQPGVVY KHAYF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [708-1041]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LGRHEAKFEL LEKLRLRCSG SDNVIATPNL TMKFCGKDDK PPVANNNVLP ILIHSCPDDF  60
   61 STVDYFDNLK TEHIGRLVIY APVVSSSMHL INNLELIHGL AVLPVQQTSG VGRRNNQWLS 120
  121 PPGCAMFSLQ LHLTMDSALS SRLPLLQHLV GTAIVNSLRS HEEYGVLDIS IKWPNDIYAN 180
  181 GNQKIGGLVI NTTLQGSQAI VNIGSGINLN NSRPTVCIND LIREYNTRVP NNKLPILKYE 240
  241 LLIAMIFNEI ERLLGEVQNG DFDSFYALYY SLWLHSGQSV KICLQKDQEK EAEIVGIDDF 300
  301 GFLEVKLPTG TIEIVQPDGN SFDMLKGLII PKYQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 85.09691
Match: 1biaA
Description: THE E. COLI BIOTIN HOLOENZYME SYNTHETASE(SLASH)BIO REPRESSOR CRYSTAL STRUCTURE DELINEATES THE BIOTIN AND DNA-BINDING DOMAINS
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
aminoacyl-tRNA ligase activity 4.025601351766 bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds 4.02412423650651 bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds 4.02412423650651 bayes_pls_golite062009
ligase activity 3.51191116674556 bayes_pls_golite062009
catalytic activity 1.99372273395202 bayes_pls_golite062009
phenylalanine-tRNA ligase activity 0.685157827624735 bayes_pls_golite062009
sequence-specific DNA binding 0.66129822977065 bayes_pls_golite062009
binding 0.521863822270226 bayes_pls_golite062009
transcription activator activity 0.5042529875675 bayes_pls_golite062009
structural molecule activity 0.272316540117209 bayes_pls_golite062009
ATP binding 0.18403217430648 bayes_pls_golite062009
adenyl ribonucleotide binding 0.145955341735342 bayes_pls_golite062009
glycine-tRNA ligase activity 0.134313783036163 bayes_pls_golite062009
threonine-tRNA ligase activity 0.133891091298639 bayes_pls_golite062009
adenyl nucleotide binding 0.127823774098159 bayes_pls_golite062009
structural constituent of ribosome 0.0912115683429473 bayes_pls_golite062009
serine-tRNA ligase activity 0.0218173339521677 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle