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View Structure Prediction Details

Protein: sa-PA
Organism: Drosophila melanogaster
Length: 275 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for sa-PA.

Description E-value Query
Range
Subject
Range
gi|73972911 - gi|73972911|ref|XP_538919.2| PREDICTED: similar to taube nuss [Canis familiaris]
322.0 [0..5] [273..97]
TAF8_DANRE - Transcription initiation factor TFIID subunit 8 OS=Danio rerio GN=taf8 PE=1 SV=1
321.0 [0..5] [273..36]
gi|62654678, gi|... - gi|62654678|ref|XP_236948.3| PREDICTED: similar to taube nuss [Rattus norvegicus], gi|157816919|ref|...
319.0 [0..5] [273..32]
ENSPTRT00000057286 - null
gi|111601406, gi... - gi|55960453|emb|CAI15203.1| novel protein similar to prodos protein [Homo sapiens], gi|55959840|emb|...
314.0 [0..5] [275..34]
TAF8_XENLA - Transcription initiation factor TFIID subunit 8 OS=Xenopus laevis GN=taf8 PE=2 SV=1
309.0 [0..5] [268..24]
TAF8_BOVIN - Transcription initiation factor TFIID subunit 8 OS=Bos taurus GN=TAF8 PE=2 SV=1
309.0 [0..5] [273..34]
TAF8_XENTR - Transcription initiation factor TFIID subunit 8 OS=Xenopus tropicalis GN=taf8 PE=2 SV=1
303.0 [0..5] [268..24]
gi|68051461 - gi|68051461|gb|AAY84994.1| IP09318p [Drosophila melanogaster]
303.0 [0..1] [275..15]

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Predicted Domain #1
Region A:
Residues: [1-70]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNTYDEVLAT VLDNLLASKN CEVVDDVLRQ SMLELLRGKF REIARQTTNW SNHAGRCAPS  60
   61 YFDLERTFIR 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.0
Match: 1tafA
Description: TAF(II)42
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.83833760498314 bayes_pls_golite062009
DNA binding 2.20605244773121 bayes_pls_golite062009
nucleic acid binding 1.77431079461635 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.15400380806529 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 1.10286842697456 bayes_pls_golite062009
protein binding 1.10166468462827 bayes_pls_golite062009
transcription regulator activity 1.07001118921201 bayes_pls_golite062009
transcription factor activity 0.77822926904752 bayes_pls_golite062009
transcription activator activity 0.44852364509666 bayes_pls_golite062009
transcription cofactor activity 0.07646821147831 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [71-137]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNIKVGELKA MYEGQPDSLV LVECNAPETQ DQDFHSVPQP VLSSTKAVEL ASTTYIPDHL  60
   61 PPFPGAH

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [138-275]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TYKSSTIEKV TDRSYVAMRN RHAENELNTQ NALNQYYLRC NPNISLFEET QRDGSGHVLD  60
   61 LGPPKKLPYS DALMPRNQVF DTDIYAPIEV ITHKALDCRY LEKPKLHSSR PSSGNFEEED 120
  121 VEMEEPCSPG GLGIEKPN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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