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View Structure Prediction Details

Protein: Jafrac2-PA, Jafr...
Organism: Drosophila melanogaster
Length: 242 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Jafrac2-PA, Jafr....

Description E-value Query
Range
Subject
Range
gi|62901916 - gi|62901916|gb|AAY18909.1| thioredoxin peroxidase 1-like [synthetic construct]
253.0 [0..50] [242..30]
gi|51980440 - gb|AAH82149.1| Unknown (protein for MGC:98395) [Xenopus laevis]
PRDX2_MOUSE - Peroxiredoxin-2 OS=Mus musculus GN=Prdx2 PE=1 SV=3
251.0 [0..50] [242..6]
gi|60818622, gi|... - gi|61362999|gb|AAX42317.1| peroxiredoxin 2 [synthetic construct], gi|60818622|gb|AAX36471.1| peroxir...
PRDX2_MACFA - Peroxiredoxin-2 OS=Macaca fascicularis GN=PRDX2 PE=2 SV=3
gi|114675617 - gi|114675617|ref|XP_524127.2| PREDICTED: peroxiredoxin 2 [Pan troglodytes]
gi|109123563, gi... - gi|109123563|ref|XP_001109216.1| PREDICTED: peroxiredoxin 2 isoform 5 [Macaca mulatta], gi|109123561...
PRDX2 - peroxiredoxin 2
251.0 [0..50] [242..6]
PRDX2_CRIGR - Peroxiredoxin-2 OS=Cricetulus griseus GN=PRDX2 PE=2 SV=3
251.0 [0..52] [242..8]
gi|149037815, gi... - gi|34849738|gb|AAH58481.1| Peroxiredoxin 2 [Rattus norvegicus], gi|149037815|gb|EDL92175.1| rCG51106...
250.0 [0..52] [242..8]

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Predicted Domain #1
Region A:
Residues: [1-242]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKYLSVLLL SAALVGAAKP EDNESCYSFA GGSVYPDQPK GDHQLQYTKA VISKPAPQFE  60
   61 GTAVVNKEIV KLSLSQYLGK YVVLLFYPLD FTFVCPTEII AFSDRIAEFK KIKTEVIGVS 120
  121 VDSHFTHLAW INTPRKEGGL GDVKIPLLSD LTHKISKDYG VYLESSGHAL RGLFIIDQTG 180
  181 VLRQITMNDL PVGRSVDETI RLVQAFQYTD THGEVCPAGW RPGADTIVPN PEEKTKYFAK 240
  241 NN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 66.69897
Match: 1qmvA
Description: Thioredoxin peroxidase 2 (thioredoxin peroxidase B, 2-cys peroxiredoxin)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
alkyl hydroperoxide reductase activity 4.29610283853788 bayes_pls_golite062009
antioxidant activity 3.8464796631544 bayes_pls_golite062009
peroxidase activity 3.43831566988273 bayes_pls_golite062009
oxidoreductase activity, acting on peroxide as acceptor 3.43831566988273 bayes_pls_golite062009
selenium binding 2.92496040718744 bayes_pls_golite062009
glutathione peroxidase activity 2.56524997297011 bayes_pls_golite062009
transcription regulator activity 2.30799114442278 bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors 2.23310780102446 bayes_pls_golite062009
peroxiredoxin activity 2.12777217096121 bayes_pls_golite062009
thioredoxin peroxidase activity 1.96134566495756 bayes_pls_golite062009
protein disulfide oxidoreductase activity 1.47769936616412 bayes_pls_golite062009
disulfide oxidoreductase activity 1.32811008894503 bayes_pls_golite062009
binding 1.25802922431343 bayes_pls_golite062009
protein binding 1.18479617596618 bayes_pls_golite062009
molecular transducer activity 1.11518182894524 bayes_pls_golite062009
signal transducer activity 1.11518182894524 bayes_pls_golite062009
catalytic activity 0.672192331361968 bayes_pls_golite062009
peptide binding 0.374493676068876 bayes_pls_golite062009
0.359224524631956 bayes_pls_golite062009
NADH dehydrogenase activity 0.23291471505999 bayes_pls_golite062009
copper ion binding 0.178842772364502 bayes_pls_golite062009
NADH dehydrogenase (ubiquinone) activity 0.16328723676608 bayes_pls_golite062009
NADH dehydrogenase (quinone) activity 0.0434052164026002 bayes_pls_golite062009

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