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View Structure Prediction Details

Protein: gol-PB
Organism: Drosophila melanogaster
Length: 461 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gol-PB.

Description E-value Query
Range
Subject
Range
gi|125809513, gi... - gi|54636324|gb|EAL25727.1| GA15425-PA [Drosophila pseudoobscura], gi|125809513|ref|XP_001361150.1| G...
283.0 [0..1] [459..1]

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Predicted Domain #1
Region A:
Residues: [1-163]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYIRKTLLLA CLVLLFGGLP PLTFPATTTT LVAAMSIANQ DLERYFRPGN GTHSFSGMED  60
   61 RIAVDVYNYA FLNWSYVEHG NMLCNMEFAQ EQARYGEGKV LNVTGRLIHI TATDNFSDDY 120
  121 ACTPYIRGTL GAPIPDKGET WIALVRRGRC TFEEKVKHVY QQN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.69897
Match: 1xf1A
Description: Structure of C5a peptidase- a key virulence factor from Streptococcus
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [164-356]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AAGVIIYNDK QVMQLEKMQI KGKTRNIAAV ITYQNIGQDL SLTLDKGYNV TISIIEGRRG  60
   61 VRTISSLNRT SVLFVSISFI VLMIISLVWL IFYYIQRFRY MQAKDQQSRN LCSVTKKAIM 120
  121 KIPTKTGKFS DEKDLDSDCC AICIEAYKPT DTIRILPCKH EFHKNCIDPW LIEHRTCPMC 180
  181 KLDVLKFYGY VFL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.0
Match: 1fbvA
Description: Cbl; N-terminal domain of cbl (N-cbl); CBL
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 3.12724619324809 bayes_pls_golite062009
transcription regulator activity 2.32209932468336 bayes_pls_golite062009
protein binding 2.14586566310919 bayes_pls_golite062009
nucleic acid binding 2.09146786953566 bayes_pls_golite062009
DNA binding 1.92481088182068 bayes_pls_golite062009
transcription factor activity 1.22542472051838 bayes_pls_golite062009
calcium ion binding 0.9587727543737 bayes_pls_golite062009
molecular adaptor activity 0.494024302340603 bayes_pls_golite062009
SH3/SH2 adaptor activity 0.409062479526042 bayes_pls_golite062009
protein binding, bridging 0.370788151516215 bayes_pls_golite062009
signal transducer activity 0.150891693412241 bayes_pls_golite062009
molecular transducer activity 0.150891693412241 bayes_pls_golite062009
cytoskeletal protein binding 0.0128369896420697 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [357-461]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSEESILEYQ PDPPQGLALV EARDESADLN RSRDFVVDFP RVFVLDSGCV VGAREMLFPC  60
   61 RIPERSQSSL SLRQARDWVS LMSNKLEEQQ GLRSMRNDEM QQVIK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle