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View Structure Prediction Details

Protein: CG4563-PA
Organism: Drosophila melanogaster
Length: 537 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG4563-PA.

Description E-value Query
Range
Subject
Range
gi|77996178, gi|... - gi|78044063|ref|YP_360551.1| long-chain-fatty-acid--CoA ligase [Carboxydothermus hydrogenoformans Z-...
533.0 [0..11] [534..7]

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Predicted Domain #1
Region A:
Residues: [1-537]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPTKAVFPTF FNKETQVWSG PPRPTVYDHN TSVGQIVFNS LRCWPTNVIQ ITDDDGTVLT  60
   61 NADMLAYATR IALFFKSEGL TQEDRVGIIA NSSTFVIPVA TACFFQATPF HAVNYSREPA 120
  121 IVQGLYSVTK PKIMFIDGPD YDRIKEITKE WSPKLITLTG KVEGVTSIED LVKPHPAEKI 180
  181 YVPASLATGG DQIAVVLCSS GTAGLPKAVA LSHRHIASTN SLCISTDVLY TSATIDWMTG 240
  241 FSITVMNLTC GFTRIISRRT FSAETALYLV SKYKVTCLAM APWQAYELFT SPLATSEQLE 300
  301 SLKIAFVIGG WISLALLRRA QELLPKTYVM FSYGTTETGV VTINIDHSLE CSVGRLAPGM 360
  361 RIKIQGEDGQ QLGVNQTGEV LIDIGLKWEG YLSNPEDTAT TLQDGWINLG DLGYFDEDNN 420
  421 LYLVDRKKDL LKYKSKHYWP NEIEQIIAEL PEVEHVCVVG VRDARYGDAA GALIIKKEGA 480
  481 EIADQKVIDH VAQRVVVDYK QLNAGVIFVD KFPKNANGKV MRSLAREVFE KTKPITF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 108.0
Match: 1ba3A
Description: FIREFLY LUCIFERASE IN COMPLEX WITH BROMOFORM
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
fatty acid ligase activity 4.83067429373059 bayes_pls_golite062009
long-chain fatty acid-CoA ligase activity 4.72692389032116 bayes_pls_golite062009
ligase activity, forming carbon-sulfur bonds 3.29836010446023 bayes_pls_golite062009
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) 2.74744781333102 bayes_pls_golite062009
Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activity 2.74744781333102 bayes_pls_golite062009
luciferin monooxygenase activity 2.67396462766343 bayes_pls_golite062009
ligase activity 2.49556073715112 bayes_pls_golite062009
transcription regulator activity 2.31193176808353 bayes_pls_golite062009
acetate-CoA ligase activity 1.84544471242521 bayes_pls_golite062009
catalytic activity 1.83545185797733 bayes_pls_golite062009
acid-thiol ligase activity 1.68632853816656 bayes_pls_golite062009
binding 1.5312519256537 bayes_pls_golite062009
CoA-ligase activity 1.40182631742133 bayes_pls_golite062009
transcription repressor activity 1.2638869228049 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle