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View Structure Prediction Details

Protein: Alas-PA
Organism: Drosophila melanogaster
Length: 539 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Alas-PA.

Description E-value Query
Range
Subject
Range
gi|19527643 - gi|19527643|gb|AAL89936.1| SD01515p [Drosophila melanogaster]
481.0 [0..1] [539..1]

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Predicted Domain #1
Region A:
Residues: [1-92]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQCPFLNRFT ASFIRNYAET LCQSYGSHCP VVGKTLVSGE KKLSLVAASV TRSHSTGANA  60
   61 HANAGGPATA NATAPVSAPA SADPGKASAK ET

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [93-539]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FPYERFFNEQ IMKKKRDHSY RVFKKVNRLA GDGLFPHALE YSERTEKPIT VWCSNDYLGM  60
   61 SAHPGVKRAV QDALNRHGSG AGGTRNISGN SLHHERLESK LAELHQKEAA LLFTSCFVAN 120
  121 DSTLFTLAKL LPGCEIFSDA GNHASMIMGI RNSGVPKHIF RHNDVDHLHQ LLKQTDKSVP 180
  181 KIVAFETVHS MTGAICPLEE LLDVAHEHGA ITFIDEVHAV GLYGDHGAGV GERDGVLHKM 240
  241 DIISGTLGKA FGNIGGYIAG THNLVDMIRS YAAGFIFTTS LPPTVLCGAL EAVNILASEE 300
  301 GRQLRHLHQR NVSYLKSLLK REGFPVEETP SHIIPIKIGD PLKSSQISNV LIEQFGHYLQ 360
  361 SINYPTVARG QEKLRLAPTP FHTFEMMNAL VTDLKKVWEM VDLSTNVPLS PNACMFCNSE 420
  421 SCWHQDTSPD LECGIPNCPR LEISLAA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 90.522879
Match: 2bwnA
Description: 5-Aminolevulinate Synthase from Rhodobacter capsulatus
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
C-palmitoyltransferase activity 9.1839236553858 bayes_pls_golite062009
serine C-palmitoyltransferase activity 9.1839236553858 bayes_pls_golite062009
C-acyltransferase activity 4.29379571948906 bayes_pls_golite062009
L-aspartate:2-oxoglutarate aminotransferase activity 3.359406422625 bayes_pls_golite062009
5-aminolevulinate synthase activity 3.15163480353521 bayes_pls_golite062009
catalytic activity 2.29878871754893 bayes_pls_golite062009
N-succinyltransferase activity 1.81799375593294 bayes_pls_golite062009
threonine aldolase activity 1.80396420390785 bayes_pls_golite062009
adenosylmethionine-8-amino-7-oxononanoate transaminase activity 1.74778109525713 bayes_pls_golite062009
glycine dehydrogenase (decarboxylating) activity 1.46601963907552 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor 1.46601963907552 bayes_pls_golite062009
transferase activity, transferring nitrogenous groups 1.28316822767388 bayes_pls_golite062009
transaminase activity 1.24990480711889 bayes_pls_golite062009
transferase activity, transferring acyl groups 1.19150094103499 bayes_pls_golite062009
glycine C-acetyltransferase activity 0.935794708043259 bayes_pls_golite062009
transferase activity 0.737426388870721 bayes_pls_golite062009
carbon-sulfur lyase activity 0.698312655247044 bayes_pls_golite062009
intramolecular transferase activity, transferring amino groups 0.659071155545801 bayes_pls_golite062009
cystathionine beta-lyase activity 0.15938456446406 bayes_pls_golite062009
sulfurtransferase activity 0.0450490929307473 bayes_pls_golite062009

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