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View Structure Prediction Details

Protein: CG5594-PA
Organism: Drosophila melanogaster
Length: 1043 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG5594-PA.

Description E-value Query
Range		 Subject
Range
FBpp0309964, CG5... - This gene is referred to in FlyBase by the symbol Dmel\CG5594 (CG5594, FBgn0025698). It is a protein...
 821.0 [0..1] [1043..1]

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Predicted Domain #1
Region A:
Residues: [1-632] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPDRFQVTKA DEDTALDYNQ DESASGKLLG DIHDETLGEN YGSYDDSGDI HRAEENQKSS  60
   61 IDPNLYLYDD DLETRPHIST FISSIANYEN TIPAATDPDA KPAAPSARMG TLIGVFLPCI 120
  121 QNIFGVILFI RLTWVVGTAG AVCGFLIVLT CCCVTMLTAI SMSAIATNGV VPAGGSYFMI 180
  181 SRSLGPEFGG AVGMLFYTGT TLAAAMYIVG AVEIVLTYMA PWASIFGDFT KDADAMYNNF 240
  241 RVYGTLLLIF MGLIVFLGVK FVNKFATVAL ACVILSIIAV YVGIFDNIHG NEKLYMCVLG 300
  301 KRLLKDIPLE NCTKEDSFLR DIYCPDGKCE EYYLANNVTK VKGIKGLASG VFYDNIFPSF 360
  361 LEKGQFISYG KSAIDIENTS GESYNQIMAD ITTSFTLLIG IFFPSVTGIM AGSNRSGDLA 420
  421 DAQKSIPIGT ICAILTTSTV YLSSVMFFAG TVDNLLLRDK FGQSIGGKLV VANIAWPNQW 480
  481 VILIGSFLST LGAGLQSLTG APRLLQAIAR DEIIPFLAPF AKSSKRGEPT RALLLTIVIC 540
  541 QCGILLGNVD LLAPLLSMFF LMCYGFVNLA CAVQTLLRTP NWRPRFKFYH WSLSLIGLTL 600
  601 CISVMIMTSW YFALIAMGMA IIIYKYIEYR GA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.221849
Match: 1fftA
Description: Cytochrome O ubiquinol oxidase, subunit I
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
monovalent inorganic cation transmembrane transporter activity 6.93719418697328 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 6.67949994760371 bayes_pls_golite062009
cation transmembrane transporter activity 6.50939400533716 bayes_pls_golite062009
ion transmembrane transporter activity 6.40081133240949 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 6.02701109829891 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 5.9695962563814 bayes_pls_golite062009
transporter activity 4.2806100513341 bayes_pls_golite062009
transmembrane transporter activity 4.19885907933483 bayes_pls_golite062009
substrate-specific transporter activity 4.09889747645813 bayes_pls_golite062009
binding 1.32681091506724 bayes_pls_golite062009
heme-copper terminal oxidase activity 1.27735515053931 bayes_pls_golite062009
copper ion binding 1.08782819178001 bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors 0.803860393147327 bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors, oxygen as acceptor 0.803860393147327 bayes_pls_golite062009
cytochrome-c oxidase activity 0.803860393147327 bayes_pls_golite062009
active transmembrane transporter activity 0.349031670056176 bayes_pls_golite062009
primary active transmembrane transporter activity 0.336122020727214 bayes_pls_golite062009
protein binding 0.335149649581279 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [633-679] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EKEWGDGIRG MALTAARYSL LRLEEGPPHT KNWRPQILVL SKLNDNL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.522879
Match: 1m57A
Description: Bacterial aa3 type cytochrome c oxidase subunit I
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [680-845] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPKYRKIFSF ATQLKAGKGL TICVSVIKGD HTKITNKAVD AKATLRKYMT DEKVKGFCDV  60
   61 LVAQQIGEGL SSVIQTIGLG GMKPNTVIIG WPYSWRQEGR NSWKTFIQTV RTVAACHMAL 120
  121 MVPKGINFYP ESNHKIGGNI DIWWIVHDGG LLMLLPFLLK QHRTWR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [846-963] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NCKLRIFTVA QIEDNSIQMK KDLKTFLYHL RIEADVEVVE MNNSDISAYT YERTLMMEQR  60
   61 NQMLRALGLN KKENSKVDSQ NDEKRNSIDL DGPENADTPE TTSNKDESTE KADGDFKS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [964-1043] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SVKPDEFNVR RMHTAIKLNE VIVEKSQDAQ LVIMNLPGPP REVRAERERN YMEFLEVLTE  60
   61 GLEKVLMVRG GGREVITIYS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

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Created and Maintained by: Michael Riffle