YRC Public Data Repository - Protein Structure Prediction

Protein:	mRpL43-PA
Organism:	Drosophila melanogaster
Length:	192 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mRpL43-PA.

Description	E-value	Query Range	Subject Range
gi\|125809329, gi... - gi\|54636251\|gb\|EAL25654.1\| GA18912 [Drosophila pseudoobscura pseudoobscura], gi\|125809329\|ref\|XP_001... gi\|54636251\|gb\|E... - GA18912-PA [Drosophila pseudoobscura], GA18912 [Drosophila pseudoobscura pseudoobscura] gi\|194114017, gi... - gi\|195154623\|ref\|XP_002018221.1\| GL16881 [Drosophila persimilis], gi\|194114017\|gb\|EDW36060.1\| GL1688...	261.0	[0..1]	[192..1]
gi\|58375209, gi\|... - gi\|58375209\|ref\|XP_306831.2\| Anopheles gambiae str. PEST AGAP012837-PA [Anopheles gambiae str. PEST]... AGAP012837-PA - mRpL43: 39S ribosomal protein L43, mitochondrial\|protein_coding\|UNKN:33198512:33199087:1\|gene:AGAP01...	255.0	[0..1]	[182..1]
gi\|157167935, gi... - gi\|157167935\|ref\|XP_001662911.1\| 39S ribosomal protein L43 [Aedes aegypti], gi\|108881528\|gb\|EAT45753...	226.0	[0..1]	[182..1]
gi\|194390486, gi... - gi\|56462543\|emb\|CAI10918.1\| mitochondrial ribosomal protein L43 [Homo sapiens], gi\|194390486\|dbj\|BAG...	222.0	[0..10]	[163..8]
gi\|91076396 - gi\|91076396\|ref\|XP_969017.1\| PREDICTED: similar to GA18912-PA [Tribolium castaneum]	217.0	[0..1]	[192..1]

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Predicted Domain #1

Region A:
Residues: [1-114]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNSHLFLKS GFPRAPLQNG LGRYVCQLQR ITLKFCKNNG SSRGMRDFIE NHLLDFAKEN  60
   61 PGIVVYVKPR RHRTPVLVGE YLNGEREWMS CRNSTQEEIS KWIDLLKTQN GSSS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	26.69897
Match:	1s3aA
Description:	NMR Solution Structure of Subunit B8 from Human NADH-Ubiquinone Oxidoreductase Complex I (CI-B8)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
oxidoreductase activity	2.75944406275714	bayes_pls_golite062009
NADH dehydrogenase activity	1.67491903098311	bayes_pls_golite062009
NADH dehydrogenase (ubiquinone) activity	1.51076265708524	bayes_pls_golite062009
NADH dehydrogenase (quinone) activity	1.38563210321556	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH	1.05291982801016	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor	0.7678907195493	bayes_pls_golite062009
binding	0.680816432660797	bayes_pls_golite062009
catalytic activity	0.672192331361968	bayes_pls_golite062009
transcription regulator activity	0.364698672137451	bayes_pls_golite062009
protein binding	0.341730456502484	bayes_pls_golite062009
	0.0102370745096865	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [115-192]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SLRLRKMWHT EVPSIQGPWT PFLLRSPDAQ GQAYPSAEAS KPLDTPQTAT EKLIELFRQQ  60
   61 QLEAGEEAHD VLNKKRAE

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: