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View Structure Prediction Details

Protein: mRpL43-PA
Organism: Drosophila melanogaster
Length: 192 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mRpL43-PA.

Description E-value Query
Range
Subject
Range
gi|125809329, gi... - gi|54636251|gb|EAL25654.1| GA18912 [Drosophila pseudoobscura pseudoobscura], gi|125809329|ref|XP_001...
gi|54636251|gb|E... - GA18912-PA [Drosophila pseudoobscura], GA18912 [Drosophila pseudoobscura pseudoobscura]
gi|194114017, gi... - gi|195154623|ref|XP_002018221.1| GL16881 [Drosophila persimilis], gi|194114017|gb|EDW36060.1| GL1688...
261.0 [0..1] [192..1]
gi|58375209, gi|... - gi|58375209|ref|XP_306831.2| Anopheles gambiae str. PEST AGAP012837-PA [Anopheles gambiae str. PEST]...
AGAP012837-PA - mRpL43: 39S ribosomal protein L43, mitochondrial|protein_coding|UNKN:33198512:33199087:1|gene:AGAP01...
255.0 [0..1] [182..1]
gi|157167935, gi... - gi|157167935|ref|XP_001662911.1| 39S ribosomal protein L43 [Aedes aegypti], gi|108881528|gb|EAT45753...
226.0 [0..1] [182..1]
gi|194390486, gi... - gi|56462543|emb|CAI10918.1| mitochondrial ribosomal protein L43 [Homo sapiens], gi|194390486|dbj|BAG...
222.0 [0..10] [163..8]
gi|91076396 - gi|91076396|ref|XP_969017.1| PREDICTED: similar to GA18912-PA [Tribolium castaneum]
217.0 [0..1] [192..1]

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Predicted Domain #1
Region A:
Residues: [1-114]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNSHLFLKS GFPRAPLQNG LGRYVCQLQR ITLKFCKNNG SSRGMRDFIE NHLLDFAKEN  60
   61 PGIVVYVKPR RHRTPVLVGE YLNGEREWMS CRNSTQEEIS KWIDLLKTQN GSSS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 26.69897
Match: 1s3aA
Description: NMR Solution Structure of Subunit B8 from Human NADH-Ubiquinone Oxidoreductase Complex I (CI-B8)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
oxidoreductase activity 2.75944406275714 bayes_pls_golite062009
NADH dehydrogenase activity 1.67491903098311 bayes_pls_golite062009
NADH dehydrogenase (ubiquinone) activity 1.51076265708524 bayes_pls_golite062009
NADH dehydrogenase (quinone) activity 1.38563210321556 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH 1.05291982801016 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor 0.7678907195493 bayes_pls_golite062009
binding 0.680816432660797 bayes_pls_golite062009
catalytic activity 0.672192331361968 bayes_pls_golite062009
transcription regulator activity 0.364698672137451 bayes_pls_golite062009
protein binding 0.341730456502484 bayes_pls_golite062009
0.0102370745096865 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [115-192]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SLRLRKMWHT EVPSIQGPWT PFLLRSPDAQ GQAYPSAEAS KPLDTPQTAT EKLIELFRQQ  60
   61 QLEAGEEAHD VLNKKRAE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.505 N/A N/A a.60.5 Barrier-to-autointegration factor, BAF
View Download 0.501 N/A N/A a.64.1 Saposin
View Download 0.465 N/A N/A a.144.1 PABC (PABP) domain
View Download 0.366 N/A N/A d.16.1 FAD-linked reductases, C-terminal domain
View Download 0.306 N/A N/A a.46.1 Methionine synthase domain


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle