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View Structure Prediction Details

Protein: stl-PA
Organism: Drosophila melanogaster
Length: 790 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for stl-PA.

Description E-value Query
Range
Subject
Range
FBpp0292546 - type=protein; loc=2R:join(18698897..18699017,18699565..18699708,18699808..18700043,18700216..1870105...
373.0 [0..1] [790..302]

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Predicted Domain #1
Region A:
Residues: [1-417]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQKNFPTNTE SKVVSFLLAM INGVQLLYHH PTLGRRINFV LKRLEIWKSW DPPGLVRSRD  60
   61 VENYLNSFCK WQEKLNPFSD ADPLHYDHAL VLTGLDLVTY DKGKANSQVV GMATVKGMCT 120
  121 SIYSCTINEA KHFESVFVVA HEIGHNLGMR HDAKEISCDP TMHIMSPKLG SGKVTWSKCS 180
  181 RTYLEDFLMD PQAECLFDRD SFAGPWDHTA GGRLPGERFN ANQQCMLRFG KNFMQASTQS 240
  241 KMEICRDLHC RQDGLPWTSH PALEGTECGP NMWCRGGTCE ARSSKQGSYS ALKSWPPEHI 300
  301 PEATHEKIIR HEPNRIPPLL HDYNPMDNEL PGSPSNWGEW SEPSACESGC LYGQSRRLLE 360
  361 GSTGLRTLNR SCLNFPSRCI GRDRRFVTCN TPQCHKVPVQ TINDFATQVC MQARKSD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 29.39794
Match: 2dw0A
Description: No description for 2dw0A was found.

Predicted Domain #2
Region A:
Residues: [418-496]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PELTGEGQQL PSTLDASCKI FCRTRTNGTK SRRWTFPDGT TCKAKQHNPE DITYCISGRC  60
   61 ERFSCDNSTS NFFKMDSSF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.045757
Match: 1n7dA
Description: Low density lipoprotein (LDL) receptor YWTD domain; Low density lipoprotein (LDL) receptor, different EGF domains; Ligand-binding domain of low-density lipoprotein receptor
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [497-706]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CEARSVRPTR DSSDQESRQQ TNRQRYAERQ EGKPQKNHYE NEVAKRPSYG QGNHINAPAS  60
   61 PYKRRNYHKP YPPEIPRPPP PASASLIALD RSSSSESEWV AHPGCHSNCM TDSKGVQGVT 120
  121 SRLTGVESIQ LCSYRIQPCE RLQTAAEYAE QTCARYRQKV RGLSGHGAQI SASIDEPDRS 180
  181 CRVGCQDEFI KYRYYLVNGR NGHFPPGTRC 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.69897
Match: 2dtgE
Description: No description for 2dtgE was found.

Predicted functions:

Term Confidence Notes
growth factor binding 4.48551849237988 bayes_pls_golite062009
insulin-like growth factor binding 3.58732804029568 bayes_pls_golite062009
insulin-like growth factor I binding 2.62174059145613 bayes_pls_golite062009
binding 2.00958032287792 bayes_pls_golite062009
protein binding 1.6400967625441 bayes_pls_golite062009
insulin-like growth factor II binding 0.48009413670884 bayes_pls_golite062009
catalytic activity 0.271811389148807 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [707-790]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPVGKRYCVY GRCLEFGDDD LPLDKTHISL GQLRTRRKRS SISNDLFNIT EIFIKPSHSD  60
   61 ISAENIEFTQ PIHVSADELS SKSR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle