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View Structure Prediction Details

Protein: CG3875-PA, FBpp0...
Organism: Drosophila melanogaster
Length: 340 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG3875-PA, FBpp0....

Description E-value Query
Range
Subject
Range
gi|16198253, gi|... - gi|24658069|ref|NP_477306.2| quaking related 58E-3 CG3584-PA [Drosophila melanogaster], gi|21626562|...
306.0 [0..1] [325..4]

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Predicted Domain #1
Region A:
Residues: [1-65]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 METQSEFTEE QNQDQPTQDQ PTYQPRLNEV AQKFLADLDE ERKRLSAEFP LCALLIDESV  60
   61 DRVFS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [66-221]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TGRIPGKEFY ADVYHQRPMK ITQKVFVPVN KFPKFNFARK ILGPKGNSVR RLKEETNCKI  60
   61 VIKGRSSMRD RNKEEELRSS GDPRYAHLHK DLFLEVSAVA PPAECYARIA YALAEIRKYL 120
  121 IPDDNDDVWH EQQRELMEMN PESAKKSNGL NMAPYR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 48.39794
Match: 2bl5A
Description: Solution structure of the KH-QUA2 region of the Xenopus STAR-GSG Quaking protein.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 4.04366657586229 bayes_pls_golite062009
nucleic acid binding 2.9975833546175 bayes_pls_golite062009
protein binding 2.23982167381721 bayes_pls_golite062009
RNA binding 1.92480731732573 bayes_pls_golite062009
mRNA binding 0.492861030614662 bayes_pls_golite062009
transcription regulator activity 0.441650663459137 bayes_pls_golite062009
DNA binding 0.355450873947182 bayes_pls_golite062009
catalytic activity 0.113112541746059 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [222-340]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SIFDKTIGGN RNGAPKYNNQ IRRVTENPRE VADMEEVEYD YDEHRMPPSR PSLGFEYSKP  60
   61 PPSMTATNAT PFKRAYPYPT DMNRTREPPI KSYKPNPYTI LNKYINNRAP SDFVAQRYN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle