YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: a-PC, a-PA, a-PB
Organism: Drosophila melanogaster
Length: 1329 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for a-PC, a-PA, a-PB.

Description E-value Query
Range
Subject
Range
gi|54637236, gi|... - gi|54637236|gb|EAL26639.1| GA19824-PA [Drosophila pseudoobscura], gi|125811948|ref|XP_001362059.1| G...
570.0 [0..50] [1328..1]

Back

Predicted Domain #1
Region A:
Residues: [1-239]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRLFKTRKST DTYSTLAAQQ QQQQQQQQQH QAEGSNISHS SNSSSNKSHT PATCSNRLNK  60
   61 SIVSSTSISS SLPDLHDKSP VMILSCTTLA SNGATATAAV TATATGTAAT SGGSLQQQQQ 120
  121 QHLQHQQQQQ PLRTATPTCL LSGRQTPSAI SVMSLQEATS LHRQQQQPHQ PPTIYVPVPT 180
  181 KLGNNVNTGN SSATLLLSYG STSSIANLQQ QQQQHAAQYQ QYVAQRLHAA SSSCLYEKG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [240-349]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNASGGASSN KSSLSLTPNG HLPDYKLVTA MPVVVLDDEH KSNSLPATEA SRNSNSSSNM  60
   61 NGSSNSNSLD VSNSNSHSGS STSLASTTRN VFTWGKRMSR KLDLLKRSDS 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [350-538]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PAAAHKSHSD LRSLFHSPTH HKSGSGGSSG PSSAKASASP TGGHQNSSGS TTSTLKKCKS  60
   61 GPIETIKQRH QQQQQQQQSV QDVGTGQSQS AQSTPTHQFQ AAARPQKALK NFFHRIGSTG 120
  121 MLNHRSHNLL KASEAAQQAT PAATTLYRSS STSQLSSSSY VKCDDPTEGL NLQREQREQR 180
  181 LPRIASLKS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [539-749]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSCDDIAKVS SCLTASTSSG SAAGSLGSPP SSAAAGGGGT ANSGQHDPSR RGAFPYAFLR  60
   61 SRLSVLPEEN HGNVPGHLKQ QIQRQREQHQ QHQRDLLQQE QTSSPLPQRR SPEQAMLNNV 120
  121 SRNDSITSKD WEPLYQRLSS CLSSNESGYD SDGGATGARL GNNLSISGGD TESIASGTLK 180
  181 RNSLISLSSS EGVGMGMGMS LGLGAPSTRN S

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [750-895]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SICSAPVSLG GYNYDYETET IRRRFRQVKL ERKCQEDYIG IVLSPKTVMT NSNEQQYRYL  60
   61 IVELEPYGMA QKDGRLRLGD EIVNVNGKHL RGIQSFAEVQ RLLSSFVDNC IDLVIAHDEV 120
  121 TTVTDFYTKI RIDGMSTQRH RLSYVQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.69897
Match: 1ueqA
Description: Solution Structure of The First PDZ domain of Human Atrophin-1 Interacting Protein 1 (KIAA0705 protein)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein binding 2.3816879009135 bayes_pls_golite062009
binding 2.18285297573892 bayes_pls_golite062009
receptor binding 0.237609767198544 bayes_pls_golite062009
protein domain specific binding 0.16193472434519 bayes_pls_golite062009

Predicted Domain #6
Region A:
Residues: [896-1110]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RTQSTDSLSS MQSLQLQQER IQGHNTEQEQ EAQGEDQCDA RSMASVSTMP TPMPLMQHRR  60
   61 SSTPRHSLDV GAPEHELLRR RARSSSGQRS LALTPTPLFA SGSSSCSSSP NHRLLDNEND 120
  121 PANDTDSYTP VYANRAASVC VASSLADDEK WQLLARKRCS EGSALSATPN PQQFGQRTHY 180
  181 ARNSINLANS HYRSLRFAHS RLSSSRLSLF MQAPP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [1111-1208]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NSLTVGEGVA NTPSSTATTT TDLTNQQQQQ QNQQQTHQSL YIKHSPKSVS LFSPNPYVNA  60
   61 SSSPASASTS AGAGSSLAPP AAALMHHRPS LPVAKLTI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #8
Region A:
Residues: [1209-1329]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RDEEMAEVIR ASMSEGSGRC TPKTITFFKG PGLKSLGFSI VGGRDSPKGN MGIFVKTVFP  60
   61 SGQAADDGTL QAGDEIVEIN GNSVQGMSHA ETIGLFKNVR EGTIVLKILR RKLQKAKSMG 120
  121 C

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.522879
Match: 2fneA
Description: The crystal structure of the 13th PDZ domain of MPDZ
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle