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View Structure Prediction Details

Protein: FBpp0309676, FBp...
Organism: Drosophila melanogaster
Length: 1202 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0309676, FBp....

Description E-value Query
Range
Subject
Range
gi|15278182 - gi|15278182|gb|AAK94064.1|AF401654_1 MAGI-1B alpha beta [Homo sapiens]
394.0 [0..128] [1133..141]

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Predicted Domain #1
Region A:
Residues: [1-149]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPIITATTTS TAGGGAGVAA RGVATAKSPT DYLMLQQQQQ QQQQQQQHFN SNHFYQQQQP  60
   61 QQLAPLNASH QHQHSHPHPH PHPVAAATSF ATFNGNSNLN SSLANGSSRK FNCSRDNVDD 120
  121 GGDAGEMAAA SQTLSSAGTD VVGNGSGHG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.221849
Match: 2nq3A
Description: No description for 2nq3A was found.

Predicted functions:

Term Confidence Notes
binding 0.781337143228833 bayes_pls_golite062009
protein binding 0.227131692236443 bayes_pls_golite062009
lipid binding 0.0337768015719 bayes_pls_golite062009
phospholipid binding 0.0300488593105301 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [150-261]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NGTVTGNGEK SGGLAPPGGH HLRPPPPPAL KKSASAVIGN SASREDVASL SGTSSLNSQM  60
   61 SVHNQFISGL PSNGIGSNGV HGGAATGRGG PPNSILKGSK ENLLQNTYYN GE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [262-425]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TGDSSLGSEC GVGDVQHQNH ESHDDPGDGL GPLPPKWETA YTERGELYFI DHNTGTSHWL  60
   61 DPRLSKYQKK SLEDCCEDEL PYGWEKIEDS MYGMYFIDHV NRRTQYENPV LEAKRRAAEQ 120
  121 SQQQQQMQQQ QQQMQEQRSK TPTALSETMP TEAAEAHEQE EDES

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 4.48
Match: 1tk7A
Description: NMR structure of WW domains (WW3-4) from Suppressor of Deltex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.567217058965138 bayes_pls_golite062009
protein binding 0.258202703637397 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [426-584]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PMKLPYKFTR NPAELQGQRI NTTLLKSSRG LGFTIVGSDG SAGGDVEEFL QIKTVVPNGP  60
   61 AWLDGQLQTG DVLVYVNDTC VLGYTHHDMV NIFQSILPGE RAALEVCRGY PLPFDPNDPN 120
  121 TEVVTTMAVD GRESDKQRRL NMDGNYNFLD LSGEGAKKT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.522879
Match: 1ueqA
Description: Solution Structure of The First PDZ domain of Human Atrophin-1 Interacting Protein 1 (KIAA0705 protein)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.2660260398866 bayes_pls_golite062009
protein binding 1.24671577203404 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [585-689]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGSGSGFILM KKPEIYTFSI MKGSMGFGFT IADSACGQIV KKILDRNCCT QLMEGDVLLE  60
   61 INGLNVRNKP HFYVVELLKE CSQTTPTAVK IQRTPPDPPA NNTLA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10.154902
Match: 1ujvA
Description: Solution structure of the second PDZ domain of human membrane associated guanylate kinase inverted-2 (MAGI-2)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.2660260398866 bayes_pls_golite062009
protein binding 1.24671577203404 bayes_pls_golite062009

Predicted Domain #6
Region A:
Residues: [690-916]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QLNQVGNVAK LRKNFVGSGL FRSKTPTADL YSTQVKEVLP MRPKTPLVDT RRSRVQIQSP  60
   61 NNEVDDEGDG AAAAERKPLQ LQTQGKSNSS LQELDDIPYM DPYPKISRLS ERLAEVTLQG 120
  121 DANGGIYGMP PSMQPLPLPL AHHESCYCYD CQAQRYRPGY FVQAQQAAMS GTTGQYSPLQ 180
  181 TAHLQNERIQ RRVNELLSDR RRVGFANLDP PQQMQHSPSW RNGALLD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [917-1019]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VSEDADQCEL TEVTLERQAL GFGFRIVGGT EEGSQVTVGH IVPGGAADQD QRINTGDEIL  60
   61 SIDGINVLNS SHHKVVSLVG ESALRGQVTM ILRRRRTPLL QQA

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 4.02
Match: 1z87A
Description: solution structure of the split PH-PDZ Supramodule of alpha-Syntrophin
Matching Structure (courtesy of the PDB):

Predicted Domain #8
Region A:
Residues: [1020-1202]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PVSTQLRRYP YDVIVSRHEN EGFGFVIISS SNHYYGSTIG KLIPGSPADR CGELKVGDRI  60
   61 VAVNRIEIAG MSHGDVVNLI KESGLHVRLT IGVPLKEGGP SPGGSSVGVS SNTPLQASPS 120
  121 LLKAQLSHQQ QLPQQHLQQA QLNHHHQHLE MPMSMPVPGH GSYLERPSNN ISATLALHQQ 180
  181 PQL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.0
Match: 1uewA
Description: Solution Structure of The forth PDZ Domain of Human Atrophin-1 Interacting Protein 1 (KIAA0705 Protein)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.2660260398866 bayes_pls_golite062009
protein binding 1.24671577203404 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle