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View Structure Prediction Details

Protein: FBpp0309676, FBp...
Organism: Drosophila melanogaster
Length: 1202 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0309676, FBp....

Description E-value Query
Range
Subject
Range
gi|15278182 - gi|15278182|gb|AAK94064.1|AF401654_1 MAGI-1B alpha beta [Homo sapiens]
394.0 [0..128] [1133..141]

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Predicted Domain #1
Region A:
Residues: [1-149]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPIITATTTS TAGGGAGVAA RGVATAKSPT DYLMLQQQQQ QQQQQQQHFN SNHFYQQQQP  60
   61 QQLAPLNASH QHQHSHPHPH PHPVAAATSF ATFNGNSNLN SSLANGSSRK FNCSRDNVDD 120
  121 GGDAGEMAAA SQTLSSAGTD VVGNGSGHG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.221849
Match: 2nq3A
Description: No description for 2nq3A was found.

Predicted functions:

Term Confidence Notes
binding 0.781337143228833 bayes_pls_golite062009
protein binding 0.227131692236443 bayes_pls_golite062009
lipid binding 0.0337768015719 bayes_pls_golite062009
phospholipid binding 0.0300488593105301 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [150-261]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NGTVTGNGEK SGGLAPPGGH HLRPPPPPAL KKSASAVIGN SASREDVASL SGTSSLNSQM  60
   61 SVHNQFISGL PSNGIGSNGV HGGAATGRGG PPNSILKGSK ENLLQNTYYN GE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [262-425]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TGDSSLGSEC GVGDVQHQNH ESHDDPGDGL GPLPPKWETA YTERGELYFI DHNTGTSHWL  60
   61 DPRLSKYQKK SLEDCCEDEL PYGWEKIEDS MYGMYFIDHV NRRTQYENPV LEAKRRAAEQ 120
  121 SQQQQQMQQQ QQQMQEQRSK TPTALSETMP TEAAEAHEQE EDES

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 4.48
Match: 1tk7A
Description: NMR structure of WW domains (WW3-4) from Suppressor of Deltex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.567217058965138 bayes_pls_golite062009
protein binding 0.258202703637397 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [426-584]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PMKLPYKFTR NPAELQGQRI NTTLLKSSRG LGFTIVGSDG SAGGDVEEFL QIKTVVPNGP  60
   61 AWLDGQLQTG DVLVYVNDTC VLGYTHHDMV NIFQSILPGE RAALEVCRGY PLPFDPNDPN 120
  121 TEVVTTMAVD GRESDKQRRL NMDGNYNFLD LSGEGAKKT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.522879
Match: 1ueqA
Description: Solution Structure of The First PDZ domain of Human Atrophin-1 Interacting Protein 1 (KIAA0705 protein)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.2660260398866 bayes_pls_golite062009
protein binding 1.24671577203404 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [585-689]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGSGSGFILM KKPEIYTFSI MKGSMGFGFT IADSACGQIV KKILDRNCCT QLMEGDVLLE  60
   61 INGLNVRNKP HFYVVELLKE CSQTTPTAVK IQRTPPDPPA NNTLA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10.154902
Match: 1ujvA
Description: Solution structure of the second PDZ domain of human membrane associated guanylate kinase inverted-2 (MAGI-2)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.2660260398866 bayes_pls_golite062009
protein binding 1.24671577203404 bayes_pls_golite062009

Predicted Domain #6
Region A:
Residues: [690-916]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QLNQVGNVAK LRKNFVGSGL FRSKTPTADL YSTQVKEVLP MRPKTPLVDT RRSRVQIQSP  60
   61 NNEVDDEGDG AAAAERKPLQ LQTQGKSNSS LQELDDIPYM DPYPKISRLS ERLAEVTLQG 120
  121 DANGGIYGMP PSMQPLPLPL AHHESCYCYD CQAQRYRPGY FVQAQQAAMS GTTGQYSPLQ 180
  181 TAHLQNERIQ RRVNELLSDR RRVGFANLDP PQQMQHSPSW RNGALLD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [917-1019]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VSEDADQCEL TEVTLERQAL GFGFRIVGGT EEGSQVTVGH IVPGGAADQD QRINTGDEIL  60
   61 SIDGINVLNS SHHKVVSLVG ESALRGQVTM ILRRRRTPLL QQA

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 4.02
Match: 1z87A
Description: solution structure of the split PH-PDZ Supramodule of alpha-Syntrophin
Matching Structure (courtesy of the PDB):

Predicted Domain #8
Region A:
Residues: [1020-1202]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PVSTQLRRYP YDVIVSRHEN EGFGFVIISS SNHYYGSTIG KLIPGSPADR CGELKVGDRI  60
   61 VAVNRIEIAG MSHGDVVNLI KESGLHVRLT IGVPLKEGGP SPGGSSVGVS SNTPLQASPS 120
  121 LLKAQLSHQQ QLPQQHLQQA QLNHHHQHLE MPMSMPVPGH GSYLERPSNN ISATLALHQQ 180
  181 PQL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.0
Match: 1uewA
Description: Solution Structure of The forth PDZ Domain of Human Atrophin-1 Interacting Protein 1 (KIAA0705 Protein)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.2660260398866 bayes_pls_golite062009
protein binding 1.24671577203404 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle