| Protein: | 18w-PA |
| Organism: | Drosophila melanogaster |
| Length: | 1385 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for 18w-PA.
| Description | E-value | Query Range |
Subject Range |
|
|
964.0 | [0..1] | [1385..1] |
|
Region A: Residues: [1-358] |
1 11 21 31 41 51
| | | | | |
1 MPATSSIITI IAVAACLLLL VADAHAQQQC NWQYGLTTMD IRCSVRALES GTGTPLDLQV 60
61 AEAAGRLDLQ CSQELLHASE LAPGLFRQLQ KLSELRIDAC KLQRVPPNAF EGLMSLKRLT 120
121 LESHNAVWGP GKTLELHGQS FQGLKELSEL HLGDNNIRQL PEGVWCSMPS LQLLNLTQNR 180
181 IRSAEFLGFS EKLCAGSALS NANGAVSGGS ELQTLDVSFN ELRSLPDAWG ASRLRRLQTL 240
241 SLQHNNISTL APNALAGLSS LRVLNISYNH LVSLPSEAFA GNKELRELHL QGNDLYELPK 300
301 GLLHRLEQLL VLDLSGNQLT SHHVDNSTFA GLIRLIVLNL SNNALTRIGS KTFKELYF
|
| Detection Method: |  |
| Confidence: | 42.045757 |
| Match: | 2z82A |
| Description: | No description for 2z82A was found. |
|
Region A: Residues: [359-1031] |
1 11 21 31 41 51
| | | | | |
1 LQILDMRNNS IGHIEEGAFL PLYNLHTLNL AENRLHTLDN RIFNGLYVLT KLTLNNNLVS 60
61 IVESQAFRNC SDLKELDLSS NQLTEVPEAV QDLSMLKTLD LGENQISEFK NNTFRNLNQL 120
121 TGLRLIDNRI GNITVGMFQD LPRLSVLNLA KNRIQSIERG AFDKNTEIEA IRLDKNFLTD 180
181 INGIFATLAS LLWLNLSENH LVWFDYAFIP SNLKWLDIHG NYIEALGNYY KLQEEIRVTT 240
241 LDASHNRITE IGAMSVPNSI ELLFINNNII GQIQANTFVD KTRLARVDLY ANVLSKISLN 300
301 ALRVAPVSAE KPVPEFYLGG NPFECDCSME WLQRINNLTT RQHPHVVDLG NIECLMPHSR 360
361 SAPLRPLASL SASDFVCKYE SHCPPTCHCC EYEQCECEVI CPGNCSCFHD ATWATNIVDC 420
421 GRQDLAALPN RIPQDVSDLY LDGNNMPELE VGHLTGRRNL RALYLNASNL MTLQNGSLAQ 480
481 LVNLRVLHLE NNKLTALEGT EFRSLGLLRE LYLHNNMLTH ISNATFEPLV SLEVLRLDNN 540
541 RLSSLPHLQY RHSLQGLTLG RNAWSCRCQQ LRELAQFVSD NAMVVRDAHD IYCLDAGIKR 600
601 ELELIGNLAN GPDCSDLLDA SASNISSSQD LAGGYRLPLL AAVLVLIFLV VVLIIVFVFR 660
661 ESVRMWLFAH YGV
|
| Detection Method: | |
| Confidence: | 61.09691 |
| Match: | 2a0zA |
| Description: | The molecular structure of toll-like receptor 3 ligand binding domain |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1032-1194] |
1 11 21 31 41 51
| | | | | |
1 RVCEPRFEDA GKLYDAIILH SEKDYEFVCR NIAAELEHGR PPFRLCIQQR DLPPQASHLQ 60
61 LVEGARASRK IILVLTRNLL ATEWNRIEFR NAFHESLRGL AQKLVIIEET SVSAEAEDVA 120
121 ELSPYLKSVP SNRLLTCDRY FWEKLRYAIP IELSPRGNNY TLD
|
| Detection Method: | |
| Confidence: | 49.154902 |
| Match: | 1fywA |
| Description: | Toll-like receptor 2, TLR2 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| receptor activity | 4.09933951703109 | bayes_pls_golite062009 |
| transmembrane receptor activity | 3.9640091493609 | bayes_pls_golite062009 |
| molecular transducer activity | 3.16173995936925 | bayes_pls_golite062009 |
| signal transducer activity | 3.16173995936925 | bayes_pls_golite062009 |
| binding | 2.52555346445919 | bayes_pls_golite062009 |
| nucleic acid binding | 2.35125182904603 | bayes_pls_golite062009 |
| protein binding | 2.10005190551596 | bayes_pls_golite062009 |
| lipopolysaccharide binding | 2.0324670463023 | bayes_pls_golite062009 |
| siRNA binding | 1.9040679863659 | bayes_pls_golite062009 |
| growth factor activity | 1.78996364452304 | bayes_pls_golite062009 |
| receptor binding | 1.72672102029619 | bayes_pls_golite062009 |
| 1.60235760704566 | bayes_pls_golite062009 | |
| RNA binding | 1.4672851259337 | bayes_pls_golite062009 |
| peptidoglycan binding | 1.415118707351 | bayes_pls_golite062009 |
| phosphoinositide 3-kinase binding | 1.36750739353858 | bayes_pls_golite062009 |
| pattern binding | 1.18233476165206 | bayes_pls_golite062009 |
| DNA binding | 1.14457763159383 | bayes_pls_golite062009 |
| 0.741742562203891 | bayes_pls_golite062009 | |
| double-stranded RNA binding | 0.127722958598936 | bayes_pls_golite062009 |
| growth factor binding | 0.0973189460931883 | bayes_pls_golite062009 |
| interleukin-1 receptor binding | 0.0731907516036894 | bayes_pls_golite062009 |
| lipoprotein binding | 0.02890593650353 | bayes_pls_golite062009 |
|
Region A: Residues: [1195-1385] |
1 11 21 31 41 51
| | | | | |
1 HHERFKQPVS PGMIFRQAPP PPAYYCTEEM EANYSSATTA TPSPRPTRPG GAARIVDSMP 60
61 MPMRPPSEHI YHSIESEYSA YDQHEALSMI PTGLMHQHQQ QQLRLHQQQQ QQQQQRLLQP 120
121 QFRAMPQQAI PAPSAPVHLR SGSGLSQAST STQSTAQAST SAAAAQQQQQ QQQQQAAGSE 180
181 AANKNGQAFL V
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
