YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: gi|24655858, gi|...
Organism: Drosophila melanogaster
Length: 414 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|24655858, gi|....

Description E-value Query
Range
Subject
Range
gi|76689281 - gi|76689281|ref|XP_881384.1| PREDICTED: similar to Polyadenylate-binding protein 4 (Poly(A)-binding ...
286.0 [0..18] [401..41]

Back

Predicted Domain #1
Region A:
Residues: [1-75]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPYNGASNGS GASGAGGGGA TIVVTEGPQN KKIRTGVQQP GENDVHMHAR STPQQNQQQA  60
   61 LMNKSNDDLR RKRPE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.30103
Match: 1wexA
Description: Solution structure of RRM domain in protein BAB28521
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 6.73097473547076 bayes_pls_golite062009
mRNA binding 5.29759606920196 bayes_pls_golite062009
4.67888641618755 bayes_pls_golite062009
nucleic acid binding 3.81920018903278 bayes_pls_golite062009
binding 3.49612884560266 bayes_pls_golite062009
poly-pyrimidine tract binding 3.11990160533699 bayes_pls_golite062009
single-stranded RNA binding 2.93798024346416 bayes_pls_golite062009
snRNA binding 1.76821382294389 bayes_pls_golite062009
structural molecule activity 1.29928829870122 bayes_pls_golite062009
protein binding 1.14508556628804 bayes_pls_golite062009
transcription regulator activity 1.07788694919471 bayes_pls_golite062009
DNA binding 0.978604858165557 bayes_pls_golite062009
U1 snRNA binding 0.612226940931031 bayes_pls_golite062009
mRNA 3'-UTR binding 0.591700155096213 bayes_pls_golite062009
transcription factor activity 0.234742017105535 bayes_pls_golite062009
transporter activity 0.00947930769815086 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [76-174]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TTRPNHILLF TIINPFYPIT VPEKLNVYKN EPDTSWDYTL STEPPLLGPG AAFPPFGAPE  60
   61 YHTTTPENWK GAAIHPTGLM KEPAGVVPGR NAPVAFTPQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [175-414]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GQAQGAVMMV YGLDHDTSNT DKLFNLVCLY GNVARIKFLK TKEGTAMVQM GDAVAVERCV  60
   61 QHLNNIPVGT GGKIQIAFSK QNFLSEVINP FLLPDHSPSF KEYTGSKNNR FLSPAQASKN 120
  121 RIQPPSKILH FFNTPPGLTE DQLIGIFNIK DVPATSVRLF PLKTERSSSG LIEFSNISQA 180
  181 VLAIMKCNHL PIEGKGTKFP FIMKLCFSSS KSMNGAWNNA ASEGMIEKEN EVDTKVDIYN 240
  241 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 33.0
Match: 2adcA
Description: Solution structure of Polypyrimidine Tract Binding protein RBD34 complexed with CUCUCU RNA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 6.73097473547076 bayes_pls_golite062009
mRNA binding 5.29759606920196 bayes_pls_golite062009
4.67888641618755 bayes_pls_golite062009
nucleic acid binding 3.81920018903278 bayes_pls_golite062009
binding 3.49612884560266 bayes_pls_golite062009
poly-pyrimidine tract binding 3.11990160533699 bayes_pls_golite062009
single-stranded RNA binding 2.93798024346416 bayes_pls_golite062009
snRNA binding 1.76821382294389 bayes_pls_golite062009
structural molecule activity 1.29928829870122 bayes_pls_golite062009
protein binding 1.14508556628804 bayes_pls_golite062009
transcription regulator activity 1.07788694919471 bayes_pls_golite062009
DNA binding 0.978604858165557 bayes_pls_golite062009
U1 snRNA binding 0.612226940931031 bayes_pls_golite062009
mRNA 3'-UTR binding 0.591700155096213 bayes_pls_golite062009
transcription factor activity 0.234742017105535 bayes_pls_golite062009
transporter activity 0.00947930769815086 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle