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View Structure Prediction Details

Protein: Sply-PA, Sply-PB
Organism: Drosophila melanogaster
Length: 545 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Sply-PA, Sply-PB.

Description E-value Query
Range
Subject
Range
gi|54635887, gi|... - gi|54635887|gb|EAL25290.1| GA21426 [Drosophila pseudoobscura pseudoobscura], gi|125808333|ref|XP_001...
gi|54635887|gb|E... - GA21426-PA [Drosophila pseudoobscura], GA21426 [Drosophila pseudoobscura pseudoobscura]
405.0 [0..1] [545..1]

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Predicted Domain #1
Region A:
Residues: [1-545]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRPFSGSDCL KPVTEGINRA FGAKEPWQVA TITATTVLGG VWLWTVICQD ENLYIRGKRQ  60
   61 FFKFAKKIPA VRRQVETELA KAKNDFETEI KKSNAHLTYS ETLPEKGLSK EEILRLVDEH 120
  121 LKTGHYNWRD GRVSGAVYGY KPDLVELVTE VYGKASYTNP LHADLFPGVC KMEAEVVRMA 180
  181 CNLFHGNSAS CGTMTTGGTE SIVMAMKAYR DFAREYKGIT RPNIVVPKTV HAAFDKGGQY 240
  241 FNIHVRSVDV DPETYEVDIK KFKRAINRNT ILLVGSAPNF PYGTIDDIEA IAALGVKYDI 300
  301 PVHVDACLGS FVVALVRNAG YKLRPFDFEV KGVTSISADT HKYGFAPKGS SVILYSDKKY 360
  361 KDHQFTVTTD WPGGVYGSPT VNGSRAGGII AACWATMMSF GYDGYLEATK RIVDTARYIE 420
  421 RGVRDIDGIF IFGKPATSVI ALGSNVFDIF RLSDSLCKLG WNLNALQFPS GIHLCVTDMH 480
  481 TQPGVADKFI ADVRSCTAEI MKDPGQPVVG KMALYGMAQS IPDRSVIGEV TRLFLHSMYY 540
  541 TPSQK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 47.39794
Match: 1xeyA
Description: Crystal structure of the complex of Escherichia coli GADA with glutarate at 2.05 A resolution
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
serine C-palmitoyltransferase activity 4.27273846204139 bayes_pls_golite062009
C-palmitoyltransferase activity 4.27273846204139 bayes_pls_golite062009
catalytic activity 2.29878871754893 bayes_pls_golite062009
transferase activity, transferring nitrogenous groups 1.18577404365776 bayes_pls_golite062009
transaminase activity 1.15255422926249 bayes_pls_golite062009
transferase activity 0.737426388870721 bayes_pls_golite062009
transcription regulator activity 0.691073358419788 bayes_pls_golite062009
binding 0.661198018681765 bayes_pls_golite062009
DNA binding 0.579562080072574 bayes_pls_golite062009
nucleic acid binding 0.547593348248892 bayes_pls_golite062009
C-acyltransferase activity 0.46392133442786 bayes_pls_golite062009
transcription factor activity 0.352624414131738 bayes_pls_golite062009
4-aminobutyrate transaminase activity 0.122706514261728 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle