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View Structure Prediction Details

Protein: Syn2-PE
Organism: Drosophila melanogaster
Length: 519 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Syn2-PE.

Description E-value Query
Range
Subject
Range
Syn2-PA, Syn2-PB - The gene Syntrophin-like 2 is referred to in FlyBase by the symbol Dmel\Syn2 (CG4905, FBgn0034135). ...
gi|220948752 - gi|220948752|gb|ACL86919.1| Syn2-PA [synthetic construct]
425.0 [0..6] [519..1]

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Predicted Domain #1
Region A:
Residues: [1-295]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MISGIMKLSD TMATPIEEKL DQNLKVRTGM VHVSDGKSRP EPLRLNLTME LLSLQKLEVV  60
   61 TPSSCHPNGP PMESKERMVQ ITRQKQGGLG LSIKGGAEHK LPILISRIYK DQAADITGQL 120
  121 FVGDAIIKVN GEYITACPHD DAVNILRNAG DIVVLTVKHY RAATPFLQKQ LTKDTPDSDN 180
  181 DVTCAELKAD EGYKSSVNSG TISRSCSRPM SICSEPEKRW TDVVAVPLMM AYVTRYIYGT 240
  241 DKLRQNAFEV RGLNGISTGV IHCDELAILS QWLKLITDNV VGLTHLQMKL YNRNF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 28.39794
Match: 1z87A
Description: solution structure of the split PH-PDZ Supramodule of alpha-Syntrophin
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [296-434]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AVGERIEYMG WVNEGVINNN ISWQSYKPRF LLLKGTEVML FETPPLNVAG ISKALVVYKV  60
   61 YQTMFRIVKE SETVDSRQHC FLLQSSGHEP RYLSVETRQE LLRIENSWNA AIVTSVIKLG 120
  121 RKTFAVSHHG KSGGLTLDW

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.69897
Match: 1jxmA
Description: Psd-95; Guanylate kinase-like domain of Psd-95
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [435-519]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QAGFSLTEGA ESATVWQYKF SQLRGSSDDG KSKLKLHFQD HDSRAIETKE LECQVLQSLL  60
   61 FCMHAFLTAK VASVDPAFLS SIQQT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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Created and Maintained by: Michael Riffle