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Protein Overview: Syn2-PE

General Information:
Name(s) found: Syn2-PE / FBpp0086244 [FlyBase]
Description(s) found:
Found 19 descriptions.
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  • The gene Syntrophin-like 2 is referred to in FlyBase by the symbol Dmel\Syn2 (CG4905, FBgn0034135). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:12439765..12445988. It has the cytological map location 53C7. Based on sequence similarity, it is predicted to have molecular function</span>: structural constituent of muscle; cytoskeletal protein binding. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 519 amino acids

    Gene Ontology:
    Cellular Component: syntrophin complex [ISS][NAS]
    Biological Process: NONE FOUND
    Molecular Function: structural constituent of muscle [ISS]
    protein binding [IEA]
    cytoskeletal protein binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MISGIMKLSD TMATPIEEKL DQNLKVRTGM VHVSDGKSRP EPLRLNLTME LLSLQKLEVV  60
   61 TPSSCHPNGP PMESKERMVQ ITRQKQGGLG LSIKGGAEHK LPILISRIYK DQAADITGQL 120
  121 FVGDAIIKVN GEYITACPHD DAVNILRNAG DIVVLTVKHY RAATPFLQKQ LTKDTPDSDN 180
  181 DVTCAELKAD EGYKSSVNSG TISRSCSRPM SICSEPEKRW TDVVAVPLMM AYVTRYIYGT 240
  241 DKLRQNAFEV RGLNGISTGV IHCDELAILS QWLKLITDNV VGLTHLQMKL YNRNFAVGER 300
  301 IEYMGWVNEG VINNNISWQS YKPRFLLLKG TEVMLFETPP LNVAGISKAL VVYKVYQTMF 360
  361 RIVKESETVD SRQHCFLLQS SGHEPRYLSV ETRQELLRIE NSWNAAIVTS VIKLGRKTFA 420
  421 VSHHGKSGGL TLDWQAGFSL TEGAESATVW QYKFSQLRGS SDDGKSKLKL HFQDHDSRAI 480
  481 ETKELECQVL QSLLFCMHAF LTAKVASVDP AFLSSIQQT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..295] PSI-BLAST 28.39794 solution structure of the split PH-PDZ Supramodule of alpha-Syntrophin
    2 View Details [296..434] PSI-BLAST 17.69897 Psd-95; Guanylate kinase-like domain of Psd-95
    3 View Details [435..519] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle