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Protein Overview: Syn2-PA, Syn2-PB

General Information:
Name(s) found: Syn2-PB / FBpp0086241 [FlyBase]
Syn2-PA / FBpp0086240 [FlyBase]
Description(s) found:
Found 37 descriptions.
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  • The gene Syntrophin-like 2 is referred to in FlyBase by the symbol Dmel\Syn2 (CG4905, FBgn0034135). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:12439765..12445988. It has the cytological map location 53C7. Based on sequence similarity, it is predicted to have molecular function</span>: structural constituent of muscle; cytoskeletal protein binding. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase]
  • The gene Syntrophin-like 2 is referred to in FlyBase by the symbol Dmel\Syn2 (CG4905, FBgn0034135). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:12439765..12445988. It has the cytological map location 53C7. Based on sequence similarity, it is predicted to have molecular function</span>: structural constituent of muscle; cytoskeletal protein binding. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 514 amino acids

    Gene Ontology:
    Cellular Component: syntrophin complex [ISS][NAS]
    Biological Process: NONE FOUND
    Molecular Function: structural constituent of muscle [ISS]
    protein binding [IEA]
    cytoskeletal protein binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLSDTMATP IEEKLDQNLK VRTGMVHVSD GKSRPEPLRL NLTMELLSLQ KLEVVTPSSC  60
   61 HPNGPPMESK ERMVQITRQK QGGLGLSIKG GAEHKLPILI SRIYKDQAAD ITGQLFVGDA 120
  121 IIKVNGEYIT ACPHDDAVNI LRNAGDIVVL TVKHYRAATP FLQKQLTKDT PDSDNDVTCA 180
  181 ELKADEGYKS SVNSGTISRS CSRPMSICSE PEKRWTDVVA VPLMMAYVTR YIYGTDKLRQ 240
  241 NAFEVRGLNG ISTGVIHCDE LAILSQWLKL ITDNVVGLTH LQMKLYNRNF AVGERIEYMG 300
  301 WVNEGVINNN ISWQSYKPRF LLLKGTEVML FETPPLNVAG ISKALVVYKV YQTMFRIVKE 360
  361 SETVDSRQHC FLLQSSGHEP RYLSVETRQE LLRIENSWNA AIVTSVIKLG RKTFAVSHHG 420
  421 KSGGLTLDWQ AGFSLTEGAE SATVWQYKFS QLRGSSDDGK SKLKLHFQDH DSRAIETKEL 480
  481 ECQVLQSLLF CMHAFLTAKV ASVDPAFLSS IQQT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..280] PSI-BLAST 30.0 solution structure of the split PH-PDZ Supramodule of alpha-Syntrophin
    2 View Details [281..418] PSI-BLAST 14.522879 Psd-95; Guanylate kinase-like domain of Psd-95
    3 View Details [419..514] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle