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View Structure Prediction Details

Protein: Syn2-PA, Syn2-PB
Organism: Drosophila melanogaster
Length: 514 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Syn2-PA, Syn2-PB.

Description E-value Query
Range
Subject
Range
Syn2-PE - The gene Syntrophin-like 2 is referred to in FlyBase by the symbol Dmel\Syn2 (CG4905, FBgn0034135). ...
485.0 [0..1] [514..6]

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Predicted Domain #1
Region A:
Residues: [1-280]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLSDTMATP IEEKLDQNLK VRTGMVHVSD GKSRPEPLRL NLTMELLSLQ KLEVVTPSSC  60
   61 HPNGPPMESK ERMVQITRQK QGGLGLSIKG GAEHKLPILI SRIYKDQAAD ITGQLFVGDA 120
  121 IIKVNGEYIT ACPHDDAVNI LRNAGDIVVL TVKHYRAATP FLQKQLTKDT PDSDNDVTCA 180
  181 ELKADEGYKS SVNSGTISRS CSRPMSICSE PEKRWTDVVA VPLMMAYVTR YIYGTDKLRQ 240
  241 NAFEVRGLNG ISTGVIHCDE LAILSQWLKL ITDNVVGLTH 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 30.0
Match: 1z87A
Description: solution structure of the split PH-PDZ Supramodule of alpha-Syntrophin
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [281-418]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LQMKLYNRNF AVGERIEYMG WVNEGVINNN ISWQSYKPRF LLLKGTEVML FETPPLNVAG  60
   61 ISKALVVYKV YQTMFRIVKE SETVDSRQHC FLLQSSGHEP RYLSVETRQE LLRIENSWNA 120
  121 AIVTSVIKLG RKTFAVSH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.522879
Match: 1kjwA
Description: Psd-95; Guanylate kinase-like domain of Psd-95
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [419-514]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HGKSGGLTLD WQAGFSLTEG AESATVWQYK FSQLRGSSDD GKSKLKLHFQ DHDSRAIETK  60
   61 ELECQVLQSL LFCMHAFLTA KVASVDPAFL SSIQQT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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