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View Structure Prediction Details

Protein: Rcd1-PA
Organism: Drosophila melanogaster
Length: 1001 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Rcd1-PA.

Description E-value Query
Range
Subject
Range
Rcd1-PC - The gene Reduction in Cnn dots 1 is referred to in FlyBase by the symbol Dmel\Rcd1 (CG8233, FBgn0033...
726.0 [0..68] [1001..1]

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Predicted Domain #1
Region A:
Residues: [1-494]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSFFDCFND FLQSGGNLVQ NVSQEQEQKI ADQELDGVIE LMPPTTPTPS ESSSTISAPS  60
   61 ESSFSEKMEH SYMRDTPVRS DVHNGLTPAR NILVRHPPQC PSCHTYPPQH EELSEIQQAH 120
  121 VPPYDEVVAK EAMNECARIA KYVKNNNSDE QDWVARVNKF NWTPMQEMVF EKVCSILDQD 180
  181 QLARLANDKR QHEPIHRRIS SDKSASRFRK LLASVAWESR ITQWIHALLM EHLSPSYMAS 240
  241 YLEILQTLKT KLPTLVDKML FGRPLNNSQE LLAPVMKKRW EPNIMPKSRQ LTHNAIMVVL 300
  301 PNMPTTGTVS DRMQKWYQAL STITQVVQIS LPNTNNRIGN QNLDHVAETI VSITRVKINE 360
  361 LRTENPSRGI ILVGFNAGAA LALQVALSES VACVVCMGFA YNTIRGPRGT PDDRMLDIKA 420
  421 PILFVIGQNS ARTSQEEMEG LRERMQSESS LVVVGSADDA LRVPKSKRRI EGVTQSMVDY 480
  481 MVVEEIFEFV NRTL

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 0.999
Match: 1cqzA
Description: Epoxide hydrolase, N-terminal domain; Mammalian epoxide hydrolase, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 1.12620676202498 bayes_pls_golite062009
hydrolase activity 0.756054874596198 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [495-752]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNPPGPRMPT CLMHQQGYQR LPKQSPHILA DGNANKAVQQ MRKRKMDGGL DDSMGQPSKT  60
   61 KFVPHNDAQD YGDAQTTAGG SASLPKVITP GVLGKQLPPV NLAAGTKIKM IPSSQFVQIK 120
  121 SLPSQSKLIN YTLNKPSVGT SSTANIGSVV KTLPCSSVSG QQIITLKTPS GQTQQFATAA 180
  181 TSTGAAGSST STGTGQKKYT VFKNANGMTM LHLTKSVPTT GSSSGSANMD LSNIIDMPIV 240
  241 FADNEGNIPE HQQADKDI

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [753-862]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPAPIRSANK SPLIISQKII KEANKPSGMV TSGSITAVSK PGNIVLNKGL QQLLNSSPGG  60
   61 TLATQNKVVY LNRSTIKPMG NVAPGTHRVP IRIVSTPNTG GAVTTTASSS 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [863-1001]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PIMVDPATGS KVAKTVNVQT IKPTGSVLAQ GTIRQAGNVG TKSYLQMINT APGASKTVAG  60
   61 DGKGSVRNIY FKSATGLKQL PVQMLGNRIP GGAVISSTAS ASSGSPGLRR VVNIGPVSKV 120
  121 TATSTTSSSI AATLTHNKM

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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