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View Structure Prediction Details

Protein: CG13343-PA
Organism: Drosophila melanogaster
Length: 450 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG13343-PA.

Description E-value Query
Range
Subject
Range
gi|73984884 - gi|73984884|ref|XP_864278.1| PREDICTED: similar to ubiquitin-activating enzyme E1C isoform 1 isoform...
405.0 [0..1] [444..22]

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Predicted Domain #1
Region A:
Residues: [1-450]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVHSPNPGL ILQSKRFNGL RNILEREGPF CKDGFAASSE NLEFLQTKCQ VLIIGAGGLG  60
   61 CELLKDLALM GFGNLHVIDM DTIELSNLNR QFLFRRTDIG ASKAECAARF INARVPTCRV 120
  121 TPHFKKIQDF DESFYQQFHL VVCGLDSIVA RRWINGMLLS MLRYEEDGTI DTSSIVPMID 180
  181 GGTEGFKGNA RVILPGFTAC IECTLDLFPP QVNYPLCTIA NTPRLPEHCI EYVKIIQWEK 240
  241 QNPFGVPLDG DDPQHIGWIY ERALERSNEF NITGVTYRLV QGVVKHIIPA VASTNAAIAA 300
  301 ACALEVFKLA TSCYDSMANY LNFNDLDGIY TYTYEAEKSE NCLACSNTPQ PLPIEDPNTT 360
  361 TLEDVIKLLC DSPRFQLKSP ALTTVMKDGK RRTLYMSGVK SIEEATRKNL TQSLGELGLH 420
  421 DGQQLTVTDA TSPSAMTLQL KYQSNEVEMV 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 112.0
Match: 1yovB
Description: Insights into the Ubiquitin Transfer Cascade from the refined structure of the activating enzyme for NEDD8
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
small protein activating enzyme activity 5.883593664369 bayes_pls_golite062009
NEDD8 activating enzyme activity 4.6334061288737 bayes_pls_golite062009
transcription regulator activity 2.34092044533955 bayes_pls_golite062009
small conjugating protein ligase activity 1.84216910649062 bayes_pls_golite062009
binding 1.66028321721112 bayes_pls_golite062009
transcription repressor activity 1.42083903479203 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.31244773198273 bayes_pls_golite062009
acid-amino acid ligase activity 1.27535252106053 bayes_pls_golite062009
catalytic activity 1.22201444897049 bayes_pls_golite062009
NEDD8 ligase activity 1.11310449351601 bayes_pls_golite062009
transferase activity 0.680338489823338 bayes_pls_golite062009
protein binding 0.358621954748546 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 0.302798969355962 bayes_pls_golite062009
URM1 activating enzyme activity 0.207228630005671 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle