| Protein: | Amph-PA |
| Organism: | Drosophila melanogaster |
| Length: | 602 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Amph-PA.
| Description | E-value | Query Range |
Subject Range |
|
|
308.0 | [0..1] | [602..1] |
|
Region A: Residues: [1-243] |
1 11 21 31 41 51
| | | | | |
1 MTENKGIMLA KSVQKHAGRA KEKILQNLGK VDRTADEIFD DHLNNFNRQQ ASANRLQKEF 60
61 NNYIRCVRAA QAASKTLMDS VCEIYEPQWS GYDALQAQTG ASESLWADFA HKLGDQVLIP 120
121 LNTYTGQFPE MKKKVEKRNR KLIDYDGQRH SFQNLQANAN KRKDDVKLTK GREQLEEARR 180
181 TYEILNTELH DELPALYDSR ILFLVTNLQT LFATEQVFHN ETAKIYSELE AIVDKLATES 240
241 QRG
|
| Detection Method: |  |
| Confidence: | 54.522879 |
| Match: | 1uruA |
| Description: | Amphiphysin BAR domain from Drosophila |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| cytoskeletal protein binding | 2.86582611923959 | bayes_pls_golite062009 |
| binding | 2.43584893484993 | bayes_pls_golite062009 |
| protein binding | 1.87308005875135 | bayes_pls_golite062009 |
| signal transducer activity | 1.15315260510573 | bayes_pls_golite062009 |
| molecular transducer activity | 1.15315260510573 | bayes_pls_golite062009 |
| GTPase binding | 0.50066793947946 | bayes_pls_golite062009 |
| GTPase regulator activity | 0.459881864914566 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 0.456472132383968 | bayes_pls_golite062009 |
| enzyme regulator activity | 0.180886944097381 | bayes_pls_golite062009 |
| small GTPase binding | 0.0531578648468707 | bayes_pls_golite062009 |
|
Region A: Residues: [244-330] |
1 11 21 31 41 51
| | | | | |
1 SNTLRKQTSN PIKTSSPVQS PVNKLNNANI NSNYQNQITT NGGSSLANSP TSTSSSLQEP 60
61 RFDSVSSTPE PRPESPAAAL VSATPSS
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [331-602] |
1 11 21 31 41 51
| | | | | |
1 PVENGVTTKS LERPELSGLN ASAKATTTTQ TSPTEDKAVV SEAVKPSETE GAAVAASVTP 60
61 APPATPAQIN GNNNEPSIVK EGGKQPKELP STTSNAEAAA EAAANNGNSI EEHKQKKLGN 120
121 DTTVTATETV TVTQHSVTST DTDNIVTISD TNTDTDTKTS TGTSQKGRPV PVVNRHSVNN 180
181 LNKNPFEDDD ERIYEVPADA NTADLPPGVL YRVKATYGYA KEDVDELSFE IGDLIRVIEY 240
241 DDPEDQEEGW LMGQKEGTNE KGLFPANFTR PI
|
| Detection Method: | |
| Confidence: | 15.30103 |
| Match: | 1mv3A |
| Description: | NMR STRUCTURE OF THE TUMOR SUPPRESSOR BIN1: ALTERNATIVE SPLICING IN MELANOMA AND INTERACTION WITH C-MYC |
Matching Structure (courtesy of the PDB): |
|
