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View Structure Prediction Details

Protein: Syx6-PD
Organism: Drosophila melanogaster
Length: 323 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Syx6-PD.

Description E-value Query
Range
Subject
Range
Syx6-PE - The gene Syntaxin 6 is referred to in FlyBase by the symbol Dmel\Syx6 (CG7736, FBgn0037084). It is a...
183.0 [0..12] [323..28]

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Predicted Domain #1
Region A:
Residues: [1-82]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLEDPFFVV KDEVFKALNK TRGLYLRWRE LGENGGTEAE WTTTELRNSL RSIEWDLEDL  60
   61 EDTISIVEKN PSKFRIDNRE LS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.522879
Match: 1lvfA
Description: Syntaxin 6, SNAP-25 homolog
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
SNAP receptor activity 3.50393203740159 bayes_pls_golite062009
phosphatidic acid binding 2.19104724611902 bayes_pls_golite062009
binding 2.13344290488739 bayes_pls_golite062009
SNARE binding 1.85060343142976 bayes_pls_golite062009
transporter activity 1.74189664015129 bayes_pls_golite062009
protein binding 1.51700626946713 bayes_pls_golite062009
substrate-specific transporter activity 1.2360389745429 bayes_pls_golite062009
transmembrane transporter activity 1.13101548288086 bayes_pls_golite062009
protein transporter activity 0.81087535212264 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.398018181744571 bayes_pls_golite062009
extracellular ligand-gated ion channel activity 0.27873535382283 bayes_pls_golite062009
excitatory extracellular ligand-gated ion channel activity 0.27873535382283 bayes_pls_golite062009
ion transmembrane transporter activity 0.0981818568206971 bayes_pls_golite062009
phospholipid binding 0.0172309833091902 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [83-232]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SRRHFIDNTR DEVKQMKDKM SLNRSRDRDI TAHQPLLDND RHSPNHNHSI AIPNSNSNSN  60
   61 EYHQHPHNDR TYLVECPNGN SLINSGSQVA NTIAGTMSAA AAAASRHSGT KYSKLENALD 120
  121 SPSHYGQTHH GGMDSPSHRY VGETVSIQQR 

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.79
Match: 2npsD
Description: No description for 2npsD was found.

Predicted Domain #3
Region A:
Residues: [233-323]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIQGQDEQLD MISDSIGTLK TVSRQIGVEL DEQAVMLDDF GNEFDTTESK LDTTMKKVAK  60
   61 VLHMNNDKRQ WAAILILSGL LLFVIILFII L

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.39794
Match: 2npsD
Description: No description for 2npsD was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle