YRC Public Data Repository - Protein Structure Prediction

Protein:	FBpp0304270, cag-PA
Organism:	Drosophila melanogaster
Length:	225 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0304270, cag-PA.

Description	E-value	Query Range	Subject Range
gi\|1785942 - gi\|1785942\|gb\|AAB41049.1\| CAG [Drosophila melanogaster]	208.0	[0..1]	[225..1]
gi\|109087630 - gi\|109087630\|ref\|XP_001083291.1\| PREDICTED: similar to jerky homolog isoform 3 [Macaca mulatta]	185.0	[0..7]	[198..14]
gi\|27694109, gi\|... - gi\|27694109\|gb\|AAH43351.1\| JRK protein [Homo sapiens], gi\|22208999\|ref\|NP_003715.1\| jerky homolog [H...	185.0	[0..7]	[198..14]
gi\|55631372, gi\|... - gi\|55631372\|ref\|XP_528246.1\| PREDICTED: jerky homolog isoform 3 [Pan troglodytes], gi\|114622036\|ref\|...	183.0	[0..7]	[198..14]
gi\|57095656 - gi\|57095656\|ref\|XP_539188.1\| PREDICTED: similar to jerky homolog [Canis familiaris]	182.0	[0..3]	[195..10]
gi\|183396933 - gi\|183396933\|gb\|AAI66010.1\| Jerky [synthetic construct] JERKY_MOUSE - Jerky protein OS=Mus musculus GN=Jrk PE=2 SV=2	180.0	[0..7]	[199..14]

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Predicted Domain #1

Region A:
Residues: [1-141]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSGRVRKPR TSLTLEEKME VIQSQERNKL SVRDLAKRFN IGKTQAADIL KHKQSIKEGL  60
   61 LSGELKLNQM RRNPLSQRGA QIDEMCFDWF SRVRTENIPI SGEMVRKKAK QLAVELGHSN 120
  121 FSASSGWLEK WRKRHNVRYN D

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	25.0
Match:	1hlvA
Description:	DNA-binding domain of centromere binding protein B (CENP-B)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	0.334577365229545	bayes_pls_golite062009
transcription regulator activity	0.0696342306231097	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [142-225]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TGDSLDLQEF EAILVKSEPI SNKDDCDEPY PVTLIEPIYS TEEAMMQLAR LKEFAKDDYA  60
   61 SYQQLISLEN QWSWKWNIFK KELP

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.882	a.144.1	PABC (PABP) domain

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: