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View Structure Prediction Details

Protein: Su(var)2-10-PI
Organism: Drosophila melanogaster
Length: 640 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Su(var)2-10-PI.

Description E-value Query
Range
Subject
Range
gi|220950582 - gi|220950582|gb|ACL87834.1| Su(var)2-10-PA [synthetic construct]
Su(var)2-10-PD - The gene Suppressor of variegation 2-10 is referred to in FlyBase by the symbol Dmel\Su(var)2-10 (CG...
559.0 [0..1] [565..1]

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Predicted Domain #1
Region A:
Residues: [1-102]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRKTRSQTAR TQAENAATSS SPGHQSTSSA PIAVNPFDST KYKECEQMVQ MLRVVELQKI  60
   61 LSFLNISFAG RKTDLQSRIL SFLRTNLELL APKVQEVYAQ SV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.69897
Match: 1v66A
Description: Solution structure of human p53 binding domain of PIAS-1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleic acid binding 3.06883460395012 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [103-195]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QEQNATLQYI DPTRMYSHIQ LPPTVQPNPV GLVGSGQGVQ VPGGQMNVVG GAPFLHTHSI  60
   61 NSQLPIHPDV RLKKLAFYDV LGTLIKPSTL VPR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [196-353]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NTQRVQEVPF YFTLTPQQAT EIASNRDIRN SSKVEHAIQV QLRFCLVETS CDQEDCFPPN  60
   61 VNVKVNNKLC QLPNVIPTNR PNVEPKRPPR PVNVTSNVKL SPTVTNTITV QWCPDYTRSY 120
  121 CLAVYLVKKL TSTQLLQRMK TKGVKPADYT RGLIKEKL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [354-449]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TEDADCEIAT TMLKVSLNCP LGKMKMLLPC RASTCSHLQC FDASLYLQMN ERKPTWNCPV  60
   61 CDKPAIYDNL VIDGYFQEVL GSSLLKSDDT EIQLHQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.0
Match: 2yu4A
Description: No description for 2yu4A was found.

Predicted Domain #5
Region A:
Residues: [450-640]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DGSWSTPGLR SETQILDTPS KPAQKVEVIS DDIELISDDA KPVKRDLSPA QDEQPTSTSN  60
   61 SETVDLTLSD SDDDMPLAKR RPPAKQAVAS STSNGSGGGQ RAYTPAQQPQ QSESPEQQAS 120
  121 RQSPEKQTVS EQQLQQQQHE QPATAAVHAS LLESLAAAVA DQKHFQLLDL AAVAAAAAAT 180
  181 ASSGQSQNAG P

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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