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View Structure Prediction Details

Protein: Pabp2-PA, Pabp2-PB
Organism: Drosophila melanogaster
Length: 224 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Pabp2-PA, Pabp2-PB.

Description E-value Query
Range		 Subject
Range
gi|13560783 - gi|13560783|gb|AAK30205.1|AF349964_1 poly(A)-binding protein [Daucus carota]
 165.0 [0..3] [221..225]
gi|92873940 - gi|92873940|gb|ABE82276.1| RNA-binding region RNP-1 (RNA recognition motif) [Medicago truncatula]
 162.0 [0..3] [223..219]
gi|76689285 - gi|76689285|ref|XP_881509.1| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 2 ...
 161.0 [0..1] [223..195]
gi|73976799 - gi|73976799|ref|XP_857739.1| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 2 ...
 161.0 [0..1] [223..195]
gi|55959639, gi|... - gi|66267552|gb|AAH94755.1| PABPC4 protein [Homo sapiens], gi|55962217|emb|CAI12298.1| poly(A) bindin...
gi|114555673 - gi|114555673|ref|XP_001170937.1| PREDICTED: poly A binding protein, cytoplasmic 4 isoform 1 [Pan tro...
 161.0 [0..1] [223..195]
gi|48734702 - gi|48734702|gb|AAH71591.1| PABPC4 protein [Homo sapiens]
 161.0 [0..1] [223..195]
gi|109002439 - gi|109002439|ref|XP_001113342.1| PREDICTED: poly A binding protein, cytoplasmic 4 [Macaca mulatta]
CCDS438.1_1 - null
 161.0 [0..1] [223..195]

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Predicted Domain #1
Region A:
Residues: [1-224] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADEDITLNE DQLLESLEET NGEQETEIAT EVEEEGSMQI DPELEAIKAR VKEMEEEAEK  60
   61 IKQMQSEVDK QMAGGSTTGL ATVPLSLEEK QEIDTRSVYV GNVDYGASAE ELEAHFHGCG 120
  121 TINRVTILCN KADGHPKGFA YIEFGSKEFV ETALAMNETL FRGRQIKVMS KRTNRPGLST 180
  181 TNRFARGSFR GRGARVSRAC CHSTFRGARR AMGYRGRANY YAPY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 37.154902
Match: 1pgzA
Description: Crystal Structure of UP1 Complexed With d(TTAGGGTTAG(6-MI)G); A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6-MI)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 5.15097136329571 bayes_pls_golite062009
mRNA binding 4.05281507540116 bayes_pls_golite062009
nucleic acid binding 3.81920018903278 bayes_pls_golite062009
binding 3.05116833253954 bayes_pls_golite062009
2.60920363363072 bayes_pls_golite062009
single-stranded RNA binding 1.46469774223879 bayes_pls_golite062009
poly-pyrimidine tract binding 1.36691748240059 bayes_pls_golite062009
transcription regulator activity 1.07788694919471 bayes_pls_golite062009
DNA binding 0.978604858165557 bayes_pls_golite062009
mRNA 3'-UTR binding 0.591700155096213 bayes_pls_golite062009
protein binding 0.42571879933058 bayes_pls_golite062009
transcription factor activity 0.234742017105535 bayes_pls_golite062009
hydrolase activity 0.153089401492248 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
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