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View Structure Prediction Details

Protein: debcl-PA
Organism: Drosophila melanogaster
Length: 300 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for debcl-PA.

Description E-value Query
Range
Subject
Range
gi|6724090 - gi|6724090|gb|AAF26841.1|AF149798_1 Bcl-2 family member protein [Drosophila melanogaster]
326.0 [0..1] [300..26]

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Predicted Domain #1
Region A:
Residues: [1-300]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPTTSPPPK LAKFKSSSLD HEIYTANRRG TIATASSDWK ALRGGVGGGA GGPGSVPNPS  60
   61 NGRSLHAGGP MTRAASTSSL ASSTRTMTNY QEYKMDIINQ GKCLCGQYIR ARLRRAGVLN 120
  121 RKVTQRLRNI LDPGSSHVVY EVFPALNSMG EELERMHPRV YTNISRQLSR APFGELEDSD 180
  181 MAPMLLNLVA KDLFRSSITW GKIISIFAVC GGFAIDCVRQ GHFDYLQCLI DGLAEIIEDD 240
  241 LVYWLIDNGG WLGLSRHIRP RVGEFTFLGW LTLFVTISAG AYMVSNVCRR IGGQLYSLLF 300
  301 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 46.045757
Match: 1f16A
Description: Proapoptotic molecule Bax
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
BH3 domain binding 6.43959332849655 bayes_pls_golite062009
BH domain binding 5.99641721040442 bayes_pls_golite062009
death domain binding 4.8394058973128 bayes_pls_golite062009
protein binding 3.0436105050182 bayes_pls_golite062009
binding 2.59561200514645 bayes_pls_golite062009
protein heterodimerization activity 2.08481887850766 bayes_pls_golite062009
protein dimerization activity 2.02084894683525 bayes_pls_golite062009
transporter activity 1.34634197931778 bayes_pls_golite062009
transmembrane transporter activity 1.13326310611172 bayes_pls_golite062009
caspase inhibitor activity 1.1117246440194 bayes_pls_golite062009
protein channel activity 0.982298120724541 bayes_pls_golite062009
identical protein binding 0.674037751773281 bayes_pls_golite062009
substrate-specific transporter activity 0.628766142173243 bayes_pls_golite062009
protein transporter activity 0.472388332659106 bayes_pls_golite062009
cysteine-type endopeptidase inhibitor activity 0.450804017765264 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.401540458357579 bayes_pls_golite062009
caspase regulator activity 0.287831586746878 bayes_pls_golite062009
protein transmembrane transporter activity 0.0896822837562903 bayes_pls_golite062009
transcription activator activity 0.055978531291871 bayes_pls_golite062009
transcription regulator activity 0.0304736434950499 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle