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View Structure Prediction Details

Protein: giac-PA
Organism: Drosophila melanogaster
Length: 273 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for giac-PA.

Description E-value Query
Range
Subject
Range
gi|3882341 - gi|3882341|dbj|BAA34530.1| KIAA0810 protein [Homo sapiens]
253.0 [0..27] [271..545]
gi|76616953 - gi|76616953|ref|XP_875817.1| PREDICTED: similar to Sad1/unc-84-like protein 2 (Rab5-interacting prot...
252.0 [0..5] [271..847]
gi|50953790 - gi|50953790|gb|AAT90501.1| SUN1 [Mus musculus]
252.0 [0..4] [271..551]
gi|73969598 - gi|73969598|ref|XP_538371.2| PREDICTED: similar to Sad1/unc-84-like protein 2 (Rab5 interacting prot...
252.0 [0..5] [271..644]

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Predicted Domain #1
Region A:
Residues: [1-106]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAHNSRNNLG IMRLREDVDD ISHILRQQQI DSKVAQGSCK FNCLGGEPKG VGSGMCNNRD  60
   61 VSAYVDTLFK RKIGHLMDDV YNLKKQVMSA DCSSKSAQST PKPESV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [107-273]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ALAKPRINYA SEELGARIIN VKAHSIDGTN IIRSLLGLDF STNPPVNMIR TGLSPGSCFG  60
   61 FNGSRATVTL HLARTIIVEA ITLTHVAREM TPDLCVKSAP KNFDGLRSEN SKRELLGQWS 120
  121 YDNAANKRTQ SYSVRSDTFF RNLDFSFNSN HGANSTCIYR VEVYGRL

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.24
Match: 1tvgA
Description: X-ray structure of human PP25 gene product, HSPC034. Northeast Structural Genomics Target HR1958.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.849929350901 bayes_pls_golite062009
protein binding 0.843446597674347 bayes_pls_golite062009
integrin binding 0.389417870075603 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle