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View Structure Prediction Details

Protein: giac-PA
Organism: Drosophila melanogaster
Length: 273 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for giac-PA.

Description E-value Query
Range
Subject
Range
gi|3882341 - gi|3882341|dbj|BAA34530.1| KIAA0810 protein [Homo sapiens]
253.0 [0..27] [271..545]
gi|76616953 - gi|76616953|ref|XP_875817.1| PREDICTED: similar to Sad1/unc-84-like protein 2 (Rab5-interacting prot...
252.0 [0..5] [271..847]
gi|50953790 - gi|50953790|gb|AAT90501.1| SUN1 [Mus musculus]
252.0 [0..4] [271..551]
gi|73969598 - gi|73969598|ref|XP_538371.2| PREDICTED: similar to Sad1/unc-84-like protein 2 (Rab5 interacting prot...
252.0 [0..5] [271..644]

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Predicted Domain #1
Region A:
Residues: [1-106]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAHNSRNNLG IMRLREDVDD ISHILRQQQI DSKVAQGSCK FNCLGGEPKG VGSGMCNNRD  60
   61 VSAYVDTLFK RKIGHLMDDV YNLKKQVMSA DCSSKSAQST PKPESV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.454 a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.357 b.34.8 Fumarylacetoacetate hydrolase, FAH, N-terminal domain
View Download 0.347 a.24.17 Group V grass pollen allergen
View Download 0.324 a.118.1 ARM repeat
View Download 0.292 a.133.1 Phospholipase A2, PLA2

Predicted Domain #2
Region A:
Residues: [107-273]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ALAKPRINYA SEELGARIIN VKAHSIDGTN IIRSLLGLDF STNPPVNMIR TGLSPGSCFG  60
   61 FNGSRATVTL HLARTIIVEA ITLTHVAREM TPDLCVKSAP KNFDGLRSEN SKRELLGQWS 120
  121 YDNAANKRTQ SYSVRSDTFF RNLDFSFNSN HGANSTCIYR VEVYGRL

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.24
Match: 1tvgA
Description: X-ray structure of human PP25 gene product, HSPC034. Northeast Structural Genomics Target HR1958.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.849929350901 bayes_pls_golite062009
protein binding 0.843446597674347 bayes_pls_golite062009
integrin binding 0.389417870075603 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle