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View Structure Prediction Details

Protein: gi|27665448, gi|...
Organism: Rattus norvegicus
Length: 191 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|27665448, gi|....

Description E-value Query
Range
Subject
Range
gi|109067205 - gi|109067205|ref|XP_001095397.1| PREDICTED: similar to chromobox homolog 3 [Macaca mulatta]
201.0 [0..1] [181..270]
gi|114666540 - gi|114666540|ref|XP_523820.2| PREDICTED: similar to heterochromatin protein 1 beta [Pan troglodytes]
179.0 [0..26] [180..191]
gi|12858011 - gi|12858011|dbj|BAB31173.1| unnamed protein product [Mus musculus]
174.0 [0..1] [191..1]
gi|48146953 - gi|48146953|emb|CAG33699.1| CBX5 [Homo sapiens]
174.0 [0..1] [191..1]
gi|109488886 - gi|109488886|ref|XP_340886.3| PREDICTED: similar to Chromobox protein homolog 1 (Heterochromatin pro...
173.0 [0..26] [180..591]
gi|48249225, gi|... - gi|48374993|gb|AAT42188.1| heterochromatin protein 1 alpha [Cricetulus griseus], gi|48249225|gb|AAT4...
172.0 [0..1] [191..1]

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Predicted Domain #1
Region A:
Residues: [1-102]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKKTKRTAD SSSSEDEEEY VVEKVLDRRM VKGQVEYLLK WKGFSEEHNT WEPEKNLDCP  60
   61 ELISEFMKKY KKMKEGENNK PREKSEGNKR KSSFSNSADD IK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.045757
Match: 2d9uA
Description: No description for 2d9uA was found.

Predicted Domain #2
Region A:
Residues: [103-191]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SKKKREQSND IARGFERGLE PEKIIGATDS CGDLMFLMKW KDTDEADLVL AKEANVKCPQ  60
   61 IVIAFYEERL TWHAYPEDAE NKEKESAKS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 19.522879
Match: 1s4zA
Description: HP1 chromo shadow domain in complex with PXVXL motif of CAF-1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription repressor activity 4.08500855631983 bayes_pls_golite062009
transcription regulator activity 3.64390820819794 bayes_pls_golite062009
methylated histone residue binding 3.42338304360938 bayes_pls_golite062009
chromatin binding 3.1924157640698 bayes_pls_golite062009
binding 3.06758476214113 bayes_pls_golite062009
protein binding 2.66728689880621 bayes_pls_golite062009
nucleic acid binding 2.19167058827256 bayes_pls_golite062009
DNA binding 2.05514577638135 bayes_pls_golite062009
histone binding 2.00388175060339 bayes_pls_golite062009
transcription activator activity 1.46529895769882 bayes_pls_golite062009
sequence-specific DNA binding 1.10020047862576 bayes_pls_golite062009
DNA-dependent ATPase activity 0.998957812785999 bayes_pls_golite062009
general transcriptional repressor activity 0.75184432495983 bayes_pls_golite062009
DNA helicase activity 0.726970683178132 bayes_pls_golite062009
ATP-dependent DNA helicase activity 0.494788451379878 bayes_pls_golite062009
transcription corepressor activity 0.294457188332415 bayes_pls_golite062009
catalytic activity 0.14067200158938 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
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