YRC Public Data Repository - Protein Structure Prediction

Protein:	PGTB1_RAT
Organism:	Rattus norvegicus
Length:	377 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PGTB1_RAT.

Description	E-value	Query Range	Subject Range
gi\|108752170, gi... - gi\|110645567\|gb\|AAI18497.1\| PGGT1B protein [synthetic construct], gi\|108752170\|gb\|AAI11925.1\| PGGT1B... PGGT1B - protein geranylgeranyltransferase type I, beta subunit h0020349 - null	384.0	[0..1]	[377..1]
gi\|73970468 - gi\|73970468\|ref\|XP_538560.2\| PREDICTED: similar to protein geranylgeranyltransferase type I, beta su...	384.0	[0..1]	[377..1]
PGTB1_MOUSE - Geranylgeranyl transferase type-1 subunit beta OS=Mus musculus GN=Pggt1b PE=1 SV=1	384.0	[0..1]	[377..1]
PGTB1_BOVIN - Geranylgeranyl transferase type-1 subunit beta OS=Bos taurus GN=PGGT1B PE=2 SV=1	383.0	[0..1]	[377..1]
PGGT1B - protein geranylgeranyltransferase type I, beta subunit	382.0	[0..1]	[377..1]
gi\|114601194 - gi\|114601194\|ref\|XP_526978.2\| PREDICTED: similar to geranylgeranyltransferase type I beta-subunit [P...	381.0	[0..1]	[377..1]
gi\|89269110 - gi\|89269110\|emb\|CAJ81920.1\| protein geranylgeranyltransferase type I, beta subunit [Xenopus tropical...	346.0	[0..1]	[377..1]
gi\|67678265, gi\|... - gi\|67678265\|gb\|AAH97794.1\| MGC115505 protein [Xenopus laevis], gi\|147907072\|ref\|NP_001089525.1\| hypo...	343.0	[0..1]	[377..1]

Back

Predicted Domain #1

Region A:
Residues: [1-377]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAATEDDRLA GSGEGERLDF LRDRHVRFFQ RCLQVLPERY SSLETSRLTI AFFALSGLDM  60
   61 LDSLDVVNKD DIIEWIYSLQ VLPTEDRSNL DRCGFRGSSY LGIPFNPSKN PGTAHPYDSG 120
  121 HIAMTYTGLS CLIILGDDLS RVDKEACLAG LRALQLEDGS FCAVPEGSEN DMRFVYCASC 180
  181 ICYMLNNWSG MDMKKAISYI RRSMSYDNGL AQGAGLESHG GSTFCGIASL CLMGKLEEVF 240
  241 SEKELNRIKR WCIMRQQNGY HGRPNKPVDT CYSFWVGATL KLLKIFQYTN FEKNRNYILS 300
  301 TQDRLVGGFA KWPDSHPDAL HAYFGICGLS LMEESGICKV HPALNVSTRT SERLRDLHQS 360
  361 WKTKDSKQCS DNVHISS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	107.0
Match:	1n4pB
Description:	Protein Geranylgeranyltransferase type-I Complexed with Geranylgeranyl Diphosphate
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
protein prenyltransferase activity	13.7736019666673	bayes_pls_golite062009
protein geranylgeranyltransferase activity	12.9757276506747	bayes_pls_golite062009
Rab geranylgeranyltransferase activity	12.8088011327065	bayes_pls_golite062009
prenyltransferase activity	11.6786310564018	bayes_pls_golite062009
CAAX-protein geranylgeranyltransferase activity	10.5569796788906	bayes_pls_golite062009
protein farnesyltransferase activity	4.15546866363415	bayes_pls_golite062009
binding	1.68564752993879	bayes_pls_golite062009
protein binding	1.45455287827127	bayes_pls_golite062009
transferase activity	1.0950430724883	bayes_pls_golite062009
enzyme regulator activity	0.854896924803117	bayes_pls_golite062009
catalytic activity	0.497699107100544	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: