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View Structure Prediction Details

Protein: CYTA_RAT
Organism: Rattus norvegicus
Length: 103 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CYTA_RAT.

Description E-value Query
Range
Subject
Range
gi|109494457 - gi|109494457|ref|XP_001070830.1| PREDICTED: similar to stefin A2 like 1 [Rattus norvegicus]
172.0 [0..1] [103..1]
gi|127140962, gi... - gi|94401232|ref|XP_998728.1| PREDICTED: similar to cystatin A [Mus musculus], gi|82965740|ref|XP_920...
161.0 [0..7] [103..1]
gi|74002880 - gi|74002880|ref|XP_545130.2| PREDICTED: similar to Cystatin A (Stefin A) (Cystatin AS) [Canis famili...
159.0 [0..2] [103..237]

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Predicted Domain #1
Region A:
Residues: [1-103]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDPGTTGIVG GVSEAKPATP EIQEVADKVK RQLEEKTNEK YEKFKVVEYK SQVVAGQILF  60
   61 MKVDVGNGRF LHMKVLRGLS GDDDLKLLDY QTNKTKNDEL TDF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 35.69897
Match: 1cyuA
Description: SOLUTION NMR STRUCTURE OF RECOMBINANT HUMAN CYSTATIN A UNDER THE CONDITION OF PH 3.8 AND 310K
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protease binding 3.05816171871392 bayes_pls_golite062009
binding 1.98021211698364 bayes_pls_golite062009
enzyme inhibitor activity 1.95903133061911 bayes_pls_golite062009
enzyme binding 1.4394131270763 bayes_pls_golite062009
cysteine-type endopeptidase inhibitor activity 1.22451594457354 bayes_pls_golite062009
protein binding 0.823288035712675 bayes_pls_golite062009
structural molecule activity 0.605570282689207 bayes_pls_golite062009
endopeptidase inhibitor activity 0.502159706024347 bayes_pls_golite062009
enzyme regulator activity 0.479748849334581 bayes_pls_golite062009
peptidase inhibitor activity 0.4067124652673 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle