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View Structure Prediction Details

Protein: LEG2_RAT
Organism: Rattus norvegicus
Length: 130 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LEG2_RAT.

Description E-value Query
Range
Subject
Range
LEG9_BOVIN - Galectin-9 OS=Bos taurus GN=LGALS9 PE=2 SV=1
161.0 [0..3] [130..16]
gi|66509265 - gi|66509265|ref|XP_392379.2| PREDICTED: similar to Galectin-4 (Lactose-binding lectin 4) (L-36 lacto...
161.0 [0..3] [130..12]
gi|27884301 - gi|27884301|dbj|BAC55887.1| galectin family xgalectin-VIIIa [Xenopus laevis]
160.0 [0..3] [129..16]
gi|4995882, gi|4... - gi|4995882|emb|CAB44279.1| urate transporter/channel protein, isoform (UATp,i) [Sus scrofa], gi|4752...
159.0 [0..1] [130..14]
gi|185134396, gi... - gi|6681410|dbj|BAA88670.1| galectin like protein [Oncorhynchus mykiss], gi|185134396|ref|NP_00111766...
158.0 [0..3] [130..15]
gi|114668564, gi... - gi|114668566|ref|XP_511349.2| PREDICTED: galectin 9 isoform 4 [Pan troglodytes], gi|114668564|ref|XP...
158.0 [0..3] [130..16]

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Predicted Domain #1
Region A:
Residues: [1-130]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEKFEVTNL NMKSGMSLKI KGKIHNDVNS FTINLGQGKE TLNLHFNPRF NESTIVCNTL  60
   61 DGSSWGQEQR ENHSCFSPGS EVKLTLTFQD KDFKVTLPDG HSLTFPNRLG HNHLRYLSMD 120
  121 GLQISSFKLE 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 31.69897
Match: 1hlcA
Description: S-lectin, different isoforms
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
sugar binding 3.34064405064299 bayes_pls_golite062009
glycosaminoglycan binding 2.70103238455595 bayes_pls_golite062009
binding 2.40096962515027 bayes_pls_golite062009
polysaccharide binding 2.35851723238763 bayes_pls_golite062009
monosaccharide binding 2.09529521879228 bayes_pls_golite062009
carbohydrate binding 1.90829797790335 bayes_pls_golite062009
protein binding 1.80794638640093 bayes_pls_golite062009
heparin binding 1.60966215355794 bayes_pls_golite062009
extracellular matrix binding 1.41229380365824 bayes_pls_golite062009
fibronectin binding 1.10309233016451 bayes_pls_golite062009
galactoside binding 1.08479183125487 bayes_pls_golite062009
pattern binding 0.969915174528009 bayes_pls_golite062009
receptor binding 0.9012250808046 bayes_pls_golite062009
extracellular matrix structural constituent 0.5068011550246 bayes_pls_golite062009
transcription regulator activity 0.372701974560119 bayes_pls_golite062009
nucleic acid binding 0.216086300988177 bayes_pls_golite062009
DNA binding 0.157628282318248 bayes_pls_golite062009
growth factor activity 0.119475011376319 bayes_pls_golite062009
fibroblast growth factor 2 binding 0.0714976455077903 bayes_pls_golite062009
fibrinogen binding 0.0714976455077903 bayes_pls_golite062009

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